Isolation and differentiation of monocytes-macrophages from human blood

Vijayan, Dipti (2012). Isolation and differentiation of monocytes-macrophages from human blood. In Robert B. Ashman (Ed.), Leucocytes: methods and protocols (pp. 183-187) New York, United States: Humana Press. doi:10.1007/978-1-61779-527-5_13


Author Vijayan, Dipti
Title of chapter Isolation and differentiation of monocytes-macrophages from human blood
Title of book Leucocytes: methods and protocols
Place of Publication New York, United States
Publisher Humana Press
Publication Year 2012
Sub-type Chapter in textbook
DOI 10.1007/978-1-61779-527-5_13
Open Access Status
Series Methods in molecular biology, v. 844
ISBN 9781617795268
9781617795275
ISSN 1064-3745
Editor Robert B. Ashman
Volume number 844
Chapter number 13
Start page 183
End page 187
Total pages 5
Total chapters 20
Collection year 2013
Language eng
Formatted Abstract/Summary
The prevalence of fungal infections remains high, and it is associated with significant mortality and morbidity. Macrophages are heterogeneous population of effectors enriched in regions of Candida colonization. These cells sense Candida, and are critical in the resolution of these infections. Here, we describe how macrophages are generated in the presence of colony-stimulating factor-1 (CSF-1); an important cytokine required for the survival, proliferation and ex-vivo differentiation of monocytes to macrophages.
Keyword Macrophages
CSF-1
Candida infections
Monocyte differentiation
Q-Index Code BX
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Wed, 26 Sep 2012, 11:36:02 EST by Ms Imogen Ferrier on behalf of Aust Institute for Bioengineering & Nanotechnology