Topical therapies for periorbital cutaneous malignancies: indications and treatment regimens

Sullivan, Timothy J. (2012) Topical therapies for periorbital cutaneous malignancies: indications and treatment regimens. Current Opinion in Ophthalmology, 23 5: 439-442. doi:10.1097/ICU.0b013e328356ad55


Author Sullivan, Timothy J.
Title Topical therapies for periorbital cutaneous malignancies: indications and treatment regimens
Journal name Current Opinion in Ophthalmology   Check publisher's open access policy
ISSN 1040-8738
1531-7021
Publication date 2012-09
Sub-type Article (original research)
DOI 10.1097/ICU.0b013e328356ad55
Open Access Status
Volume 23
Issue 5
Start page 439
End page 442
Total pages 4
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Collection year 2013
Language eng
Formatted abstract
Purpose of review: To present a brief review of periorbital cutaneous tumorogenesis, highlighting the steps which might be amenable to topical treatments and then discuss the use of topical agents in the management of periorbital skin malignancy.
Recent findings: A rapid expansion in the understanding of the pathogenesis of melanoma and nonmelanoma skin cancer has allowed the development of a number of topical agents targeting specific tumor-forming processes. Topical agents have been shown to be effective in the management of periorbital skin malignancy.
Summary: 5-Fluorouracil and imiquimod have established roles in the management of periorbital skin malignancy. Newer agents such as ingenol mebutate, tazarotene, and diclofenac gel probably have evolving roles that require further research but show promise.
Keyword 5-fluorouracil
Basal cell carcinoma
Imiquimod
Periorbital
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Medicine Publications
 
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