The confocal story

Wurm, Elisabeth M. T. and Soyer, Hans Peter (2012). The confocal story. In Rainer Hofmann-Wellenhof, Giovanni Pellacani, Joseph Malvehy and Hans Peter Soyer (Ed.), Reflectance confocal microscopy for skin diseases (pp. 3-5) Berlin, Germany: Springer.

Author Wurm, Elisabeth M. T.
Soyer, Hans Peter
Title of chapter The confocal story
Title of book Reflectance confocal microscopy for skin diseases
Place of Publication Berlin, Germany
Publisher Springer
Publication Year 2012
Sub-type Chapter in textbook
ISBN 9783642219979
Editor Rainer Hofmann-Wellenhof
Giovanni Pellacani
Joseph Malvehy
Hans Peter Soyer
Chapter number 1
Start page 3
End page 5
Total pages 3
Total chapters 37
Collection year 2013
Language eng
Abstract/Summary Dermatologic diagnosis is primarily based on interpretation of morphological information by visual inspection, confirmed by histopathological diagnosis if necessary. The challenge is to establish a correct diagnosis and to identify all malignant lesions while minimizing unnecessary surgical procedures. In this context, several non-invasive imaging modalities have emerged in recent years that are aimed at increasing accuracy of in vivo diagnosis. Of those, reflectance confocal microscopy has shown the most promising results. In vivo reflectance confocal microscopy produces horizontal images of the skin at a cellular resolution from the surface to the upper dermis. It enables to visualize tissue in its physiological state avoiding retraction bias due to fixation, staining and sectioning procedures that are a prerequisite to conventional light histopathology. Moreover, RCM enables observation of changes over time.
Q-Index Code BX
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Part 3

Document type: Book Chapter
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School of Medicine Publications
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Created: Thu, 20 Sep 2012, 16:19:16 EST by Ms Ramona Hooyer on behalf of Medicine - Princess Alexandra Hospital