Morphology, genome organization, transcription and replication of rhabdoviruses

Dietzgen, Ralf G. (2012). Morphology, genome organization, transcription and replication of rhabdoviruses. In Ralf G. Dietzgen and Ivan V. Kuzmin (Ed.), Rhabdoviruses: Molecular taxonomy, evolution, genomics, ecology, host-vector interactions, cytopathology and control (pp. 5-11) Norfolk, England, UK: Caister Academic Press.

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Name Description MIMEType Size Downloads
Author Dietzgen, Ralf G.
Title of chapter Morphology, genome organization, transcription and replication of rhabdoviruses
Title of book Rhabdoviruses: Molecular taxonomy, evolution, genomics, ecology, host-vector interactions, cytopathology and control
Place of Publication Norfolk, England, UK
Publisher Caister Academic Press
Publication Year 2012
Sub-type Chapter in textbook
ISBN 9781908230119
1908230118
Editor Ralf G. Dietzgen
Ivan V. Kuzmin
Chapter number 2
Start page 5
End page 11
Total pages 7
Total chapters 14
Collection year 2013
Language eng
Abstract/Summary Rhabdoviruses have large enveloped virions with bullet-shaped or bacilliform morphology. They are composed of an infectious nucleocapsid enveloped by a host-derived lipid membrane containing glycoprotein spikes. Their genomes consist of a non-segmented, negative-sense ssRNA which encodes at least five structural proteins. The replication cycle of all rhabdoviruses involves the same general steps. Following cell entry and uncoating, the nucleocapsid that contains all the components necessary for early transcription is released into the cytoplasm of the infected cell. The different viral genes are transcribed and proteins translated, followed by genome replication, encapsidation and budding from cell membranes.
Q-Index Code BX
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Wed, 05 Sep 2012, 14:36:00 EST by Associate Professor Ralf Dietzgen on behalf of School of Pharmacy