Structure and colon-targeted releasing property of resistant octenyl succinate starch

Li, Xiaoxi, Zhang, Panfeng, Chen, Ling, Xie, Fengwei, Li, Lin and Li, Bing (2012). Structure and colon-targeted releasing property of resistant octenyl succinate starch. In: Food Research International. 15th IUFoST World Congress of Food Science and Technology on Food Science Solutions in Evolving World, Cape Town, South Africa, (246-252). 22-26 August 2010. doi:10.1016/j.foodres.2011.06.031


Author Li, Xiaoxi
Zhang, Panfeng
Chen, Ling
Xie, Fengwei
Li, Lin
Li, Bing
Title of paper Structure and colon-targeted releasing property of resistant octenyl succinate starch
Conference name 15th IUFoST World Congress of Food Science and Technology on Food Science Solutions in Evolving World
Conference location Cape Town, South Africa
Conference dates 22-26 August 2010
Proceedings title Food Research International   Check publisher's open access policy
Journal name Food Research International   Check publisher's open access policy
Place of Publication Kidlington, Oxford, United Kingdom
Publisher Pergamon
Publication Year 2012
Sub-type Fully published paper
DOI 10.1016/j.foodres.2011.06.031
ISSN 0963-9969
1873-7145
Volume 47
Issue 2
Start page 246
End page 252
Total pages 7
Collection year 2013
Language eng
Abstract/Summary Granular and crystalline structures of resistant octenyl succinic anhydride (OSA) modified corn starch were characterized using scanning electron microscopy (SEM), optical microscopy and X-ray diffraction. As a colon-targeted delivery carrier, the releasing property of resistant OSA-modified starch was also investigated by In-vitro model. Enhanced succinylation of starch considerably increased the enzyme and acid resistibility to digestion, indicating the improvement of starch colon-targeting property as the degree of substitution (DS) increased. From In-vitro releasing assay, the resistant OSA-modified corn starch based matrix tablets could deliver bioactive components to the colon when the RS content and hydrophobicity were suitable. The relationship between the structure and In-vitro release properties of resistant OSA-modified corn starch suggests that an optimal DS and crystalline:amorphous ratio can be responsible for 5-ASA release. The matrix tablets used resistant OSA-modified corn starch with moderate DS (0.60) and V-type crystal morphology co-exist with the amorphous structure as carrier show good colon-targeted releasing properties.
Keyword Resistant starch
Octenyl-succinate modification
Bioactive food components
Colon-targeted delivery
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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