Blood dioxin biomonitoring to assess local residents' exposure from a large urban remediation project

Staff, Michael, Sheppeard, Vicky, Abeywardana, Samanthi, Forssman, Bradley, Rutherford, Alison, Mueller, Jochen F. and Paepke, Olaf (2012) Blood dioxin biomonitoring to assess local residents' exposure from a large urban remediation project. Chemosphere, 88 3: 316-322. doi:10.1016/j.chemosphere.2012.03.003


Author Staff, Michael
Sheppeard, Vicky
Abeywardana, Samanthi
Forssman, Bradley
Rutherford, Alison
Mueller, Jochen F.
Paepke, Olaf
Title Blood dioxin biomonitoring to assess local residents' exposure from a large urban remediation project
Journal name Chemosphere   Check publisher's open access policy
ISSN 0045-6535
1879-1298
Publication date 2012-07
Sub-type Article (original research)
DOI 10.1016/j.chemosphere.2012.03.003
Volume 88
Issue 3
Start page 316
End page 322
Total pages 7
Place of publication Kiddlington, Oxford, United Kingdom
Publisher Pergamon
Collection year 2013
Language eng
Formatted abstract
Background: A total of 265000m 3 of dioxin contaminated soil and sediments from past industrial activity was treated on site in an urban setting in Sydney, Australia. To respond to local community concerns about potential dioxin exposure from fugitive emissions a human biomonitoring study was undertaken.

Objective: To determine whether local residents were exposed to significant amounts of dioxin from the remediation process.

Methods: Blood samples were collected from local residents around the site and a representative metropolitan control group. They were pooled within age and sex strata and the change in dioxin concentrations over the remediation period and a summary of the mid point and post remediation dioxin concentrations were compared between groups. Information on dietary intake was collected to look for possible confounding.

Results: The mean dioxin Toxic Equivalent concentrations (TeQ) decreased among both the local resident and control groups over the remediation period by 1.9 and 2.1pggm -1 lipid respectively. Modelled blood concentrations adjusting for age and sex did not detect a significant difference between groups for changes in either TeQ or 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8 TCDD). The summary measure approach did however demonstrate that the 2,3,7,8 TCDD concentrations among the local resident group was approximately 0.7pgg -1 lipid higher compared to the control group post remediation. There were no significant changes in dietary intake sources of dioxin.

Conclusion: Biomonitoring demonstrated that local residents were not exposed to significant quantities of dioxin. Large scale remediation of dioxin contaminated land can be safely undertaken in an urban setting.
Keyword Dioxins
Tcdd
Remediation
Biomonitoring
Environmental epidemiology
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online: 6 April 2012.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
National Research Centre for Environmental Toxicology Publications
 
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