Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function: effect on short-term outcomes

Jayasekera, Hasanga, Harvey, Ryan, Pinto, Nigel, Mundy, Julie, Wood, Annabel, Beller, Elaine, Peters, Paul and Shah, Pallav (2012) Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function: effect on short-term outcomes. Heart Surgery Forum, 15 2: E69-E72. doi:10.1532/HSF98.20111155

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Author Jayasekera, Hasanga
Harvey, Ryan
Pinto, Nigel
Mundy, Julie
Wood, Annabel
Beller, Elaine
Peters, Paul
Shah, Pallav
Title Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function: effect on short-term outcomes
Journal name Heart Surgery Forum   Check publisher's open access policy
ISSN 1098-3511
1522-6662
Publication date 2012-04
Sub-type Article (original research)
DOI 10.1532/HSF98.20111155
Volume 15
Issue 2
Start page E69
End page E72
Total pages 4
Place of publication Charlottesville, VA, United States
Publisher The Heart Surgery Forum
Collection year 2013
Language eng
Formatted abstract
Background: This study evaluated the impact of decreasing renal function on short-term outcomes in patients undergoing primary coronary artery bypass grafting (CABG).

Methods: The study period was from February 1999 to February 2009. Data on 4050 patients undergoing primary CABG were prospectively collected and analyzed retrospectively. The study population was divided into 3 groups: the CABG:N group, patients with preoperative serum creatinine levels <2 mg/dL (n = 3947); the CABG:RF group, patients with preoperative creatinine levels >2 mg/dL (n = 87); and the CABG:D group, patients on dialysis (n = 16).

Results: The significant differences between the groups (CABG:D > CABG:RF > CABG:N) in short-term outcomes were with respect to blood product use (P < .001), postoperative acute myocardial infarction (P < .001), pulmonary complications (P .001), infection (P < .001), and death (P < .001). The risk of short-term death (30 days) in the CABG:D group (4/16, 25%) was 25 times greater than that in the CABG:N group (38/3947, 0.96%).

Conclusion: CABG in the presence of renal failure is associated with significant morbidity and mortality.
Keyword Chronic kidney-disease
Serum creatinine
Cardiac-surgery
Dysfunction
Mortality
Survival
Impact
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Public Health Publications
School of Medicine Publications
 
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