Acceptability and compliance of atenolol tablet, compounded paste and compounded suspension prescribed to healthy cats

Khor, Kuan Hua, Campbell, Fiona, Rathbone, Michael J., Greer, Ristan M. and Mills, Paul C. (2012) Acceptability and compliance of atenolol tablet, compounded paste and compounded suspension prescribed to healthy cats. Journal of Feline Medicine and Surgery, 14 2: 99-106.


Author Khor, Kuan Hua
Campbell, Fiona
Rathbone, Michael J.
Greer, Ristan M.
Mills, Paul C.
Title Acceptability and compliance of atenolol tablet, compounded paste and compounded suspension prescribed to healthy cats
Journal name Journal of Feline Medicine and Surgery  (ERA 2012 Listed)    (ERA 2010 Rank B)   Check publisher's open access policy
Publication date 2012-02
Sub-type Article
DOI 10.1177/1098612X11431521
Volume number 14
Issue number 2
ISSN 1532-2750
1098-612X
Start page 99
End page 106
Total pages 8
Place of publication London, United Kingdom
Publisher Sage Publications
Collection year 2013
Language eng
Abstract This study was designed to evaluate the cats' acceptance and compliance of the owners and cats towards an extemporaneously prepared palatable compounded atenolol (paste and suspension) formulation in comparison to the commercially obtained tablet, in a randomised, cross-over study design.The three formulations were prescribed twice daily for 6 days to 13 healthy privately-owned cats of 13 different owners, with varying levels of experience in medicating cats. Daily compliance was evaluated via an owner-completed diary, completed after each dose administered. Owner's experience and preference of the formulation was evaluated via questionnaires given prior to, at the end of each treatment protocol, and upon completion of the study. Although compounded suspension was association with fewest missed doses, the majority of cat owners expressed a preference for the divided tablet. Atenolol tablets, compounded paste and suspension acceptance and compliance were comparable. Further work is now required to assess the amount and stability of the active ingredient and the robustness of the paste and suspension formulations prior to any bioavailability comparisons between the formulations.
Keyword Canine plasma
HPLC
Opioid
Quantification
Tapentadol
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes All work of this study was undertaken at The University Queensland Veterinary Teaching Hospital (UQVTH), St. Lucia Campus

Document type: Journal Article
Sub-type: Article
Collections: Official 2013 Collection
School of Veterinary Science Publications
 
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Created: Fri, 06 Jul 2012, 09:37:58 EST by Ms Ramona Hooyer on behalf of School of Veterinary Science