Evidence of inter-component recombination, intra-component recombination and reassortment in banana bunchy top virus

Stainton, Daisy, Kraberger, Simona, Walters, Matthew, Wiltshire, Elizabeth J., Rosario, Karyna, Halafihi, Mana’ia, Lolohea, Samiuela, Katoa, Ika, Faitua, Tu’amelie H., Aholelei, Waikato, Taufa, Luseane, Thomas, John E., Collings, David A., Martin, Darren P. and Varsani, Arvind (2012) Evidence of inter-component recombination, intra-component recombination and reassortment in banana bunchy top virus. Journal of General Virology, 93 5: 1103-1119.


Author Stainton, Daisy
Kraberger, Simona
Walters, Matthew
Wiltshire, Elizabeth J.
Rosario, Karyna
Halafihi, Mana’ia
Lolohea, Samiuela
Katoa, Ika
Faitua, Tu’amelie H.
Aholelei, Waikato
Taufa, Luseane
Thomas, John E.
Collings, David A.
Martin, Darren P.
Varsani, Arvind
Title Evidence of inter-component recombination, intra-component recombination and reassortment in banana bunchy top virus
Journal name Journal of General Virology  (ERA 2012 Listed)    (ERA 2010 Rank A)   Check publisher's open access policy
Publication date 2012-05
Sub-type Article
DOI 10.1099/vir.0.040337-0
Volume number 93
Issue number 5
ISSN 0022-1317; 1465-2099
Start page 1103
End page 1119
Total pages 17
Place of publication Reading, United Kingdom
Publisher Society for General Microbiology
Collection year 2013
Language eng
Abstract Banana bunchy top virus (BBTV; family Nanoviridae, genus Babuvirus) is a multi-component, ssDNA virus, which causes widespread banana crop losses throughout tropical Africa and Australasia. We determined the full genome sequences of 12 BBTV isolates from the Kingdom of Tonga and analysed these together with previously determined BBTV sequences to show that reassortment and both inter- and intra-component recombination have all been relatively requent occurrences during BBTV evolution. We found that whereas DNA-U3 components display evidence of complex inter- and intra-component recombination, all of the South Pacific DNA-R components have a common intra-component recombinant origin spanning the replicationassociated protein gene. Altogether, the DNA-U3 and DNA-M components display a greater degree of inter-component recombination than the DNA-R, -S, -C and -M components. The breakpoint distribution of the inter-component recombination events reveals a primary recombination hotspot around the 59 side of the common region major and, in accordance with recombination hotspots detectable in related ssDNA viruses, a secondary recombination hotspot near the origin of virion-strand replication.
Keyword Single-Stranded-Dna
Cassava Mosaic-Virus
Nucleotide Substitution
Phylogenetic Evidence
Concerted Evolution
Genome Components
Sequence-Analysis
Disease
Geminiviruses
Nanovirus
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online ahead of print 25 January 2012.

Document type: Journal Article
Sub-type: Article
Collections: Queensland Alliance for Agriculture and Food Innovation
Official 2013 Collection
 
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