Evidence of inter-component recombination, intra-component recombination and reassortment in banana bunchy top virus

Stainton, Daisy, Kraberger, Simona, Walters, Matthew, Wiltshire, Elizabeth J., Rosario, Karyna, Halafihi, Mana’ia, Lolohea, Samiuela, Katoa, Ika, Faitua, Tu’amelie H., Aholelei, Waikato, Taufa, Luseane, Thomas, John E., Collings, David A., Martin, Darren P. and Varsani, Arvind (2012) Evidence of inter-component recombination, intra-component recombination and reassortment in banana bunchy top virus. Journal of General Virology, 93 5: 1103-1119.


Author Stainton, Daisy
Kraberger, Simona
Walters, Matthew
Wiltshire, Elizabeth J.
Rosario, Karyna
Halafihi, Mana’ia
Lolohea, Samiuela
Katoa, Ika
Faitua, Tu’amelie H.
Aholelei, Waikato
Taufa, Luseane
Thomas, John E.
Collings, David A.
Martin, Darren P.
Varsani, Arvind
Total Author Count Override 15
Title Evidence of inter-component recombination, intra-component recombination and reassortment in banana bunchy top virus
Journal name Journal of General Virology   Check publisher's open access policy
ISSN 0022-1317
1465-2099
Publication date 2012-05
Sub-type Article (original research)
DOI 10.1099/vir.0.040337-0
Volume 93
Issue 5
Start page 1103
End page 1119
Total pages 17
Place of publication Reading, United Kingdom
Publisher Society for General Microbiology
Collection year 2013
Language eng
Abstract Banana bunchy top virus (BBTV; family Nanoviridae, genus Babuvirus) is a multi-component, ssDNA virus, which causes widespread banana crop losses throughout tropical Africa and Australasia. We determined the full genome sequences of 12 BBTV isolates from the Kingdom of Tonga and analysed these together with previously determined BBTV sequences to show that reassortment and both inter- and intra-component recombination have all been relatively requent occurrences during BBTV evolution. We found that whereas DNA-U3 components display evidence of complex inter- and intra-component recombination, all of the South Pacific DNA-R components have a common intra-component recombinant origin spanning the replicationassociated protein gene. Altogether, the DNA-U3 and DNA-M components display a greater degree of inter-component recombination than the DNA-R, -S, -C and -M components. The breakpoint distribution of the inter-component recombination events reveals a primary recombination hotspot around the 59 side of the common region major and, in accordance with recombination hotspots detectable in related ssDNA viruses, a secondary recombination hotspot near the origin of virion-strand replication.
Keyword Single-Stranded-Dna
Cassava Mosaic-Virus
Nucleotide Substitution
Phylogenetic Evidence
Concerted Evolution
Genome Components
Sequence-Analysis
Disease
Geminiviruses
Nanovirus
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online ahead of print 25 January 2012.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Alliance for Agriculture and Food Innovation
Official 2013 Collection
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 10 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 11 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Access Statistics: 40 Abstract Views  -  Detailed Statistics
Created: Mon, 02 Jul 2012, 08:00:29 EST by System User on behalf of Qld Alliance for Agriculture and Food Innovation