Tramadol vs morphine during adenotonsillectomy for obstructive sleep apnea in children

Hullett, Bruce J., Chambers, Neil A., Pascoe, Elaine M. and Johnson, Chris (2006) Tramadol vs morphine during adenotonsillectomy for obstructive sleep apnea in children. Pediatric Anesthesia, 16 6: 648-653. doi:10.1111/j.1460-9592.2005.01827.x


Author Hullett, Bruce J.
Chambers, Neil A.
Pascoe, Elaine M.
Johnson, Chris
Title Tramadol vs morphine during adenotonsillectomy for obstructive sleep apnea in children
Journal name Pediatric Anesthesia   Check publisher's open access policy
ISSN 1155-5645
Publication date 2006-06
Sub-type Article (original research)
DOI 10.1111/j.1460-9592.2005.01827.x
Volume 16
Issue 6
Start page 648
End page 653
Total pages 6
Place of publication Oxford England U.K.
Publisher Wiley-Blackwell Publishing
Language eng
Formatted abstract
Background: Optimal analgesia for children undergoing adenotonsillectomy for obstructive sleep apnea (OSA) is controversial. Tramadol may represent a superior choice over morphine in this group, with a potential to cause less postoperative sedation and respiratory depression. Optimal perioperative analgesia may allow expensive and time-consuming preoperative work-up and postoperative monitoring to be rationalized. Methods: Sixty-six children were randomized to receive either perioperative tramadol or morphine in this double blinded, prospective, controlled trial. Postoperative sedation, pain, respiratory events, and vomiting were then compared between groups. Results: There was no significant difference between the two groups in sedation scores 1 h after arrival in recovery (P = 0.24) or at any other time up to 6 h postoperation. There was also no evidence of a difference between the groups in pain scores up to 6 h postoperation. There were fewer episodes of postoperative desaturation (<94%) in the tramadol group up to 3 h postoperation, with 26% fewer episodes in the tramadol group during the second hour postoperation (P = 0.02). Overall, there was a trend toward fewer desaturation episodes in the tramadol group. Conclusions: Tramadol may be a suitable drug for children undergoing adenotonsillectomy for OSA. Further work is required to investigate this
Keyword Obstructive sleep apnea
Analgesia
Adenotonsillectomy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Tue, 26 Jun 2012, 17:09:23 EST by Elaine Pascoe on behalf of School of Medicine