Evidence of spinal cord hyperexcitability as measured with nociceptive flexion reflex (NFR) threshold in chronic lateral epicondylalgia with or without a positive neurodynamic test

Lim, Edwin Choon Wyn, Sterling, Michele, Pedler, Ashley, Coombes, Brooke K. and Vicenzino, Bill (2012) Evidence of spinal cord hyperexcitability as measured with nociceptive flexion reflex (NFR) threshold in chronic lateral epicondylalgia with or without a positive neurodynamic test. Journal of Pain, 13 7: 676-684.


Author Lim, Edwin Choon Wyn
Sterling, Michele
Pedler, Ashley
Coombes, Brooke K.
Vicenzino, Bill
Title Evidence of spinal cord hyperexcitability as measured with nociceptive flexion reflex (NFR) threshold in chronic lateral epicondylalgia with or without a positive neurodynamic test
Journal name Journal of Pain  (ERA 2012 Listed)    (ERA 2010 Rank A)   Check publisher's open access policy
Publication date 2012
Sub-type Article
DOI 10.1016/j.jpain.2012.04.005
Volume number 13
Issue number 7
ISSN 1526-5900; 1528-8447
Start page 676
End page 684
Total pages 9
Place of publication Philadelphia, PA, United States
Publisher Churchill Livingstone
Collection year 2013
Language eng
Formatted abstract There is emerging evidence of altered pain signal processing as a likely underlying mechanism in chronic lateral epicondylalgia (LE), yet this remains to be assessed. Furthermore, it has been proposed that neurodynamic tests reflect nociceptive withdrawal responses. Therefore, the objective was to improve our understanding of spinal cord excitability as measured by nociceptive flexion reflex (NFR) threshold in chronic LE with and without a positive neurodynamic test. NFR threshold, pain-free grip, and pressure pain threshold were measured in 30 LE participants and 31 healthy controls. Test of neural tissue involvement (using upper limb neural tension, radial bias) was used to differentiate LE participants with or without a positive neurodynamic test. There were significant differences in NFR threshold between the control and LE with or without a positive neurodynamic test (F[2,54] = 5.68, P = .006), after adjusting for age, sex, pain rating at NFR threshold, and reflex size (NFR interval peak z score). The mean differences (95% confidence interval) in NFR threshold between the control and LE with or without a positive neurodynamic test were 3.74 mA (.637, 6.84) and 3.38 mA (.0245, 6.74) respectively.
Keyword Nociceptive flexion reflex
RIII
Pain
Tennis elbow
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online 9 June 2012

 
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Created: Mon, 25 Jun 2012, 14:25:50 EST by Chesne McGrath on behalf of Medicine - Royal Brisbane and Women's Hospital