Development in children with achondroplasia: a prospective clinical cohort study

Ireland, Penelope J., Donaghey, Samantha, McGill, James, Zankl, Andreas, Ware, Robert S., Pacey, Verity, Ault, Jenny, Savarirayan, Ravi, Sillence, David, Thompson, Elizabeth, Townshend, Sharron and Johnston, Leanne M. (2012) Development in children with achondroplasia: a prospective clinical cohort study. Developmental Medicine and Child Neurology, 54 6: 532-537. doi:10.1111/j.1469-8749.2012.04234.x

Author Ireland, Penelope J.
Donaghey, Samantha
McGill, James
Zankl, Andreas
Ware, Robert S.
Pacey, Verity
Ault, Jenny
Savarirayan, Ravi
Sillence, David
Thompson, Elizabeth
Townshend, Sharron
Johnston, Leanne M.
Title Development in children with achondroplasia: a prospective clinical cohort study
Journal name Developmental Medicine and Child Neurology   Check publisher's open access policy
ISSN 0012-1622
Publication date 2012-06
Sub-type Article (original research)
DOI 10.1111/j.1469-8749.2012.04234.x
Volume 54
Issue 6
Start page 532
End page 537
Total pages 6
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2013
Language eng
Abstract Aim Achondroplasia is characterized by delays in the development of communication and motor skills. While previously reported developmental profiles exist across gross motor, fine motor, feeding, and communication skills, there has been no prospective study of development across multiple areas simultaneously. Method This Australasian population-based study utilized a prospective questionnaire to quantify developmental data for skills in children born from 2000 to 2009. Forty-eight families from Australia and New Zealand were asked to report every 3months on their child's attainment of 41 milestones. Results include reference to previously available prospective information. Results Information from questionnaires was used to develop an achondroplasia-specific developmental recording form. The 25th, 50th, 75th, and 90th centiles were plotted to offer clear guidelines for development across gross motor, fine motor, feeding, and communication skills in children with achondroplasia. Interpretations Consistent with results from previous research, children with achondroplasia are delayed in development of gross motor and ambulatory skills. Young children with achondroplasia demonstrate a number of unique movement strategies that appear compensatory for the biomechanical changes. While delays were seen in development of later communication items, there were fewer delays seen across development of early communication, fine motor, and feeding skills.
Keyword Health Supervision
Motor Development
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article first published online: 12 March 2012.

Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 10 Jun 2012, 16:29:16 EST by System User on behalf of UQ Centre for Clinical Research