The impact of frailty and delirium on mortality in older inpatients

Eeles, Eamonn M. P., White, Susan V., O'Mahony, Sinead M., Bayer, Antony J. and Hubbard, Ruth E. (2012) The impact of frailty and delirium on mortality in older inpatients. Age and Ageing, 41 3: 412-416. doi:10.1093/ageing/afs021


Author Eeles, Eamonn M. P.
White, Susan V.
O'Mahony, Sinead M.
Bayer, Antony J.
Hubbard, Ruth E.
Title The impact of frailty and delirium on mortality in older inpatients
Journal name Age and Ageing   Check publisher's open access policy
ISSN 0002-0729
1468-2834
Publication date 2012-05
Sub-type Article (original research)
DOI 10.1093/ageing/afs021
Volume 41
Issue 3
Start page 412
End page 416
Total pages 5
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Collection year 2013
Language eng
Formatted abstract
Background: delirium and frailty are common among hospitalised older people but delirium is often missed and frailty considered difficult to measure in clinical practice.

Objective:
to explore the relationship between delirium and frailty in older inpatients and determine their impact on survival.

Design and setting:
the prospective cohort study of 273 patients aged ≥75 years.

Measures:
patients were screened for delirium at presentation and on alternate days throughout their hospital stay. Frailty status was measured by an index of accumulated deficits (FI), giving a potential score from 0 (no deficits) to 1.0 (all 33 deficits), with 0.25 used as the cut-off between ‘fit’ and ‘frail’.

Results:
delirium was detected in 102 patients (mean FI: 0.33) and excluded in 171 (mean FI: 0.18) (P < 0.005); 111 patients were frail. Among patients with delirium, the median survival in fit patients was 359 days (95% CI: 118–600) compared with 88 days for those who were frail (95% CI: 5–171; P < 0.05).

Conclusion:
delirium was associated with higher levels of frailty: the identification of frail patients may help to target those at a greatest risk of delirium. Survival following delirium was poor with the combination of frailty and delirium conferring a particularly bleak prognosis.
Keyword Delirium
Frail older adults
Survival
Elderly
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Medicine Publications
 
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