A new insight of mechanisms, diagnosis and treatment of diabetic cardiomyopathy

Zhang, Xinli and Chen, Chen (2012) A new insight of mechanisms, diagnosis and treatment of diabetic cardiomyopathy. Endocrine, 41 3: 398-409.

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Author Zhang, Xinli
Chen, Chen
Title A new insight of mechanisms, diagnosis and treatment of diabetic cardiomyopathy
Journal name Endocrine   Check publisher's open access policy
ISSN 1355-008X
1559-0100
Publication date 2012-06
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s12020-012-9623-1
Volume 41
Issue 3
Start page 398
End page 409
Total pages 12
Place of publication Totowa, NJ, United States
Publisher Humana Press
Collection year 2013
Language eng
Abstract Diabetes mellitus is one of the most common chronic diseases across the world. Cardiovascular complication is the major morbidity and mortality among the diabetic patients. Diabetic cardiomyopathy, a new entity independent of coronary artery disease or hypertension, has been increasingly recognized by clinicians and epidemiologists. Cardiac dysfunction is the major characteristic of diabetic cardiomyopathy. For a better understanding of diabetic cardiomyopathy and necessary treatment strategy, several pathological mechanisms such as impaired calcium handling and increased oxidative stress, have been proposed through clinical and experimental observations. In this review, we will discuss the development of cardiac dysfunction, the mechanisms underlying diabetic cardiomyopathy, diagnostic methods, and treatment options.
Keyword Diabetic cardiomyopathy
Cardiac dysfunction
Impaired calcium handling
Oxidative stress
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Non HERDC
School of Biomedical Sciences Publications
 
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