Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review

So, W. K. W., Chan, R. J., Chan, D. N. S., Hughes, B. G. M., Chair, S. Y., Choi, K. C. and Chan, C. W. H. (2012) Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review. European Journal of Cancer, 48 15: 2391-2408. doi:10.1016/j.ejca.2012.04.005

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Author So, W. K. W.
Chan, R. J.
Chan, D. N. S.
Hughes, B. G. M.
Chair, S. Y.
Choi, K. C.
Chan, C. W. H.
Title Quality-of-life among head and neck cancer survivors at one year after treatment: A systematic review
Journal name European Journal of Cancer   Check publisher's open access policy
ISSN 0959-8049
Publication date 2012
Sub-type Article (original research)
DOI 10.1016/j.ejca.2012.04.005
Volume 48
Issue 15
Start page 2391
End page 2408
Total pages 18
Place of publication Kidlington, Oxford, United Kingdom
Publisher Pergamon
Collection year 2013
Language eng
Formatted abstract
Background: The importance of quality-of-life (QoL) research has been recognised over the past two decades in patients with head and neck (H&N) cancer. The aims of this systematic review are to evaluate the QoL status of H&N cancer survivors one year after treatment and to identify the determinants affecting their QoL.
Methods: Pubmed, Medline, Scopus, Sciencedirect and CINAHL (2000–2011) were searched for relevant studies, and two of the present authors assessed their methodological quality. The characteristics and main findings of the studies were extracted and reported.
Results: Thirty-seven studies met the inclusion criteria, and the methodological quality of the majority was moderate to high. While patients of the group in question recover their global QoL by 12 months after treatment, a number of outstanding issues persist – deterioration in physical functioning, fatigue, xerostomia and sticky saliva. Age, cancer site, stage of disease, social support, smoking, feeding tube placement and alcohol consumption are the significant determinants of QoL at 12 months, while gender has little or no influence.
Conclusions: Regular assessments should be carried out to monitor physical functioning, degree of fatigue, xerostomia and sticky saliva. Further research is required to develop appropriate and effective interventions to deal with these issues, and thus to promote the patients’ QoL.
Keyword Cancer survivors
Critical appraisal
Head and neck cancer
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online: 11 May 2012.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Medicine Publications
School of Nursing, Midwifery and Social Work Publications
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Citation counts: TR Web of Science Citation Count  Cited 24 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 34 times in Scopus Article | Citations
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Created: Mon, 14 May 2012, 12:40:55 EST by Dr Raymond Chan on behalf of School of Nursing, Midwifery and Social Work