The burden of trachoma in South Sudan: Assessing the health losses from a condition of graded severity

Gouda, Hebe, Powles, John, Barendregt, Jan, Emerson, Paul and Ngondi, Jeremiah (2012) The burden of trachoma in South Sudan: Assessing the health losses from a condition of graded severity. PLoS Neglected Tropical Diseases, 6 3: e1538.1-e1538.7. doi:10.1371/journal.pntd.0001538


Author Gouda, Hebe
Powles, John
Barendregt, Jan
Emerson, Paul
Ngondi, Jeremiah
Title The burden of trachoma in South Sudan: Assessing the health losses from a condition of graded severity
Journal name PLoS Neglected Tropical Diseases   Check publisher's open access policy
ISSN 1935-2727
1935-2735
Publication date 2012-03
Sub-type Article (original research)
DOI 10.1371/journal.pntd.0001538
Open Access Status DOI
Volume 6
Issue 3
Start page e1538.1
End page e1538.7
Total pages 7
Place of publication San Francisco CA , United States
Publisher Public Library of Science
Collection year 2013
Language eng
Formatted abstract
Introduction: Trachoma is a disease that can lead to visual impairment and ultimately blindness. Previous estimates of health losses from trachoma using the Global Burden of Disease methodology have not, however, included the stage prior to visual impairment. We estimated the burden of all stages of trachoma in South Sudan and assessed the uncertainty associated with the severity and duration of stages of trachoma prior to full blindness.

Methods:
The prevalence of trachoma with normal vision, low vision and blindness in the Republic of South Sudan has been estimated previously. These estimates were used to model the incidence and duration of the different stages employing DISMOD II. Different assumptions about disability weights and duration were used to estimate the Years Lived with Disability (YLD).

Results: We have estimated the total burden of trachoma in South Sudan to be between 136,562 and 163,695 YLD and trichiasis with normal vision contributes between 5% and 21% of the total depending on the disability weight applied. Women experience more of this burden than men. The sensitivity of the results to different assumptions about the disability weights is partly dependent upon the assumed duration of the different disease states.

Interpretation:
A better understanding of the natural history of trachoma is critical for a more accurate burden estimate.
Keyword Global burden
Disease
Disability
Area
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number e1538

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Public Health Publications
 
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