Breast cancer risk factors in Queensland women attending population-based mammography screening

Protani, Melinda, Page, Andrew, Taylor, Richard, Glazebrook, Roz, Lahmann, Petra H., Branch, Elise and Muller, Jennifer (2012) Breast cancer risk factors in Queensland women attending population-based mammography screening. Maturitas, 71 3: 279-286. doi:10.1016/j.maturitas.2011.12.008

Author Protani, Melinda
Page, Andrew
Taylor, Richard
Glazebrook, Roz
Lahmann, Petra H.
Branch, Elise
Muller, Jennifer
Title Breast cancer risk factors in Queensland women attending population-based mammography screening
Journal name Maturitas   Check publisher's open access policy
ISSN 0378-5122
Publication date 2012-03
Sub-type Article (original research)
DOI 10.1016/j.maturitas.2011.12.008
Volume 71
Issue 3
Start page 279
End page 286
Total pages 8
Place of publication Clare, Ireland
Publisher Elsevier
Collection year 2013
Language eng
Formatted abstract
Objective: To investigate the prevalence of established modifiable and non-modifiable risk factors associated with breast cancer in Queensland (Australia) women.

Study design: Cross-sectional prevalence study of 9792 women (58% of women sent the questionnaire) attending BreastScreen Queensland Screening and Assessment Services between November 2008 and February 2009. Prevalence and 95% confidence intervals were calculated for each risk factor, stratified by age-group (45–49 years, 50–59 years, 60–69 years, ≥70 years).

Main outcome measures:
First-degree family history (FH) of breast cancer (mother, sister, daughter), reproductive history, behavioural factors, co-morbidities, use of hormone replacement therapy (HRT) and alternatives, and socio-demographic factors.

Results: The prevalence of first-degree FH of breast cancer was 16% and a previous diagnosis of breast cancer was 3.5%; both are considered major risk factors for breast cancer. The prevalence of modifiable breast cancer risk factors of moderate risk were: current HRT use (12%), HRT use within the past 5 years (7%), overweight [body mass index 25–29] (33%) or obesity [BMI > 30] (27%), alcohol consumption
[≥11 drinks/week] (10%), sedentary behaviour (70%), and low fruit (34%) and vegetable consumption (69%). These risk factors tended to be higher in younger women (45–49 years) compared to older women (>50 years).

Conclusion: Prevalence of risk factors in Queensland women were largely consistent with other Australian and international studies. Hormone therapy use is lower than previously reported estimates in Australia and internationally. The comparatively high prevalence of modifiable lifestyle factors which have been shown to be moderately associated with breast cancer are potential targets for reducing the public health
burden of breast cancer.
Keyword Breast cancer
Risk factors
Family history
Hormone replacement therapy
Complementary medicines
Reproductive factors
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
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