Antimicrobial potential of Australian macrofungi extracts against foodborne and other pathogens

Bala, Neeraj, Aitken, Elizabeth A. B., Cusack, Andrew and Steadman, Kathryn J. (2012) Antimicrobial potential of Australian macrofungi extracts against foodborne and other pathogens. Phytotherapy Research, 26 3: 465-469.


Author Bala, Neeraj
Aitken, Elizabeth A. B.
Cusack, Andrew
Steadman, Kathryn J.
Title Antimicrobial potential of Australian macrofungi extracts against foodborne and other pathogens
Journal name Phytotherapy Research  (ERA 2012 Listed)    (ERA 2010 Rank B)   Check publisher's open access policy
Publication date 2012-03
Sub-type Article
Year available 2011
DOI 10.1002/ptr.3563
Volume number 26
Issue number 3
ISSN 0951-418X; 1099-1573
Start page 465
End page 469
Total pages 5
Place of publication Bognor Regis, West Sussex, United Kingdom
Publisher John Wiley & Sons
Collection year 2012
Language eng
Formatted abstract Basidiomycetous macrofungi have therapeutic potential due to antimicrobial activity but little information is available for Australian macrofungi. Therefore, the present study investigated 12 Australian basidiomycetous macrofungi, previously shown to have promising activity against Staphylococcus aureus and Escherichia coli, for their antimicrobial potential against a range of other clinically relevant micro-organisms. Fruiting bodies were collected from across Queensland, Australia, freeze-dried and sequentially extracted with water and ethanol. The crude extracts were tested at 10 mg/mL and 1 mg/mL against six pathogens including two Gram-positive and two Gram-negative bacteria along with two fungi using a high throughput 96-well microplate bioassay. A degree of specificity in activity was exhibited by the water extract of Ramaria sp. (Gomphaceae) and the ethanol extracts of Psathyrella sp. (Psathyrellaceae) and Hohenbuehelia sp., which inhibited the growth of the two fungal pathogens used in the assay. Similarly, the ethanol extract of Fomitopsis lilacinogilva (Fomitopsidaceae) was active against the Gram-positive bacteria B. cereus only. Activity against a wider range of the microorganisms used in the assay was exhibited by the ethanol extract of Ramaria sp. and the water extract of Hohenbuehelia sp. (Pleurotaceae). These macrofungi can serve as new sources for the discovery and development of much needed new antimicrobials.
Keyword Antimicrobial activity
Mushrooms
Crude extracts
96-well microplate assay
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article first published online: 6 JUL 2011. Published under Short Communication.

Document type: Journal Article
Sub-type: Article
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