Abnormal reproductive patterns in Przewalski's mares are associated with a loss in gene diversity

Collins, C. Wynne, Songsasen, Nucharin S., Vick, Mandi M., Wolfe, Barbara A., Weiss, Rachael B., Keefer, Carol L. and Monfort, Steven L. (2012) Abnormal reproductive patterns in Przewalski's mares are associated with a loss in gene diversity. Biology of Reproduction, 86 2: 28.1-28.10. doi:10.1095/biolreprod.111.092676

Author Collins, C. Wynne
Songsasen, Nucharin S.
Vick, Mandi M.
Wolfe, Barbara A.
Weiss, Rachael B.
Keefer, Carol L.
Monfort, Steven L.
Title Abnormal reproductive patterns in Przewalski's mares are associated with a loss in gene diversity
Journal name Biology of Reproduction   Check publisher's open access policy
ISSN 0006-3363
Publication date 2012-02
Year available 2011
Sub-type Article (original research)
DOI 10.1095/biolreprod.111.092676
Volume 86
Issue 2
Start page 28.1
End page 28.10
Total pages 10
Place of publication Madison, WI, United States
Publisher Society for the Study of Reproduction
Collection year 2012
Language eng
Formatted abstract
The ex situ population of the Przewalski's horse (Equus ferus przewalskii) is not self-sustaining (20% foaling rate), and the demography is skewed toward aging individuals with low gene diversity. We designed the present study to gain a better understanding of the reproductive biology of the Przewalski's mare and to determine whether age and gene diversity influenced reproductive function. Urine samples were collected 3–7 days/wk from 19 mares from May to September, and ultrasound examinations of follicular structures were performed 3 days/wk for 5 wk from May through July in nine individuals. A high proportion of mares exhibited abnormal (endocrine, 5 [26.3%] of 19; follicular, 2 [22.2%] of 9) or acyclic (endocrine, 4 [21.1%] of 19; follicular, 3 [33.3%] of 9) reproductive patterns. In four cyclic mares, estrous cycle length was 25.1 ± 1.2 days, with 12.2 ± 0.9 days of diestrus. Follicles in cyclic mares grew 1.2 ± 0.6 mm per day and ovulated after reaching 40.4 ± 8.9 mm. Mares with a high coefficient of inbreeding excreted reduced levels of mean urinary estrogens (r2 = 0.476, P < 0.05), but age had no significant impact on reproductive patterns in this population. Overall, these data suggest that long-term genetic management of this population is necessary to maintain reproductive fitness.
Keyword Endocrinology
Equids (horses, donkeys, zebras)
Estrous cycle
Female infertility
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online before print September 7, 2011. Article # 28.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Veterinary Science Publications
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