Baseline iron indices as predictors of hemoglobin improvement in anemic Vietnamese women receiving weekly iron-folic acid supplementation and deworming

Pasricha, Sant-Rayn, Casey, Gerard J., Tran, Tran Q., Mihrshahi, Seema, MacGregor, Lachlan, Montresor, Antonio, Nong, Nong and Biggs, Beverley-Ann (2009) Baseline iron indices as predictors of hemoglobin improvement in anemic Vietnamese women receiving weekly iron-folic acid supplementation and deworming. American Journal of Tropical Medicine and Hygiene, 81 6: 1114-1119. doi:10.4269/ajtmh.2009.09-0162


Author Pasricha, Sant-Rayn
Casey, Gerard J.
Tran, Tran Q.
Mihrshahi, Seema
MacGregor, Lachlan
Montresor, Antonio
Nong, Nong
Biggs, Beverley-Ann
Title Baseline iron indices as predictors of hemoglobin improvement in anemic Vietnamese women receiving weekly iron-folic acid supplementation and deworming
Journal name American Journal of Tropical Medicine and Hygiene   Check publisher's open access policy
ISSN 0002-9637
1476-1645
Publication date 2009-12
Sub-type Article (original research)
DOI 10.4269/ajtmh.2009.09-0162
Volume 81
Issue 6
Start page 1114
End page 1119
Total pages 6
Place of publication Deerfield, IL, United States
Publisher American Society of Tropical Medicine and Hygiene
Language eng
Abstract Iron deficiency anemia is highly prevalent among women living in rural Vietnam. However, the utility and cut-offs of indices for diagnosing iron deficiency anemia in the public health context is ill defined. We assessed the ability of iron indices to predict the hemoglobin response (HBR) to weekly iron-folic acid supplementation (WIFS) in anemic rural Vietnamese women. We compared hemoglobin, serum ferritin, and soluble transferrin receptor in a cohort of 221 non-pregnant women of reproductive age before and after 3 months of WIFS and deworming. At baseline, anemia (Hb < 120 g/L) was present in 81/221 (36.7%) of subjects. After 3 months, anemia prevalence fell to 58/221 (26.2%), and the mean hemoglobin change was +3.5 g/L (95% confidence interval, 0.9, 6.6). A hemoglobin response was observed in 50/75 (66.6%) of anemic women. A ferritin cut-off < 30 ng/mL was a more sensitive predictor of response than ferritin < 15 ng/mL.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Public Health Publications
 
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