Leptospirosis in American Samoa 2010: epidemiology, environmental drivers, and the management of emergence

Lau, Colleen L., Dobson, Annettee J., Smythe, Lee D., Fearnley, Emily J., Skelly, Chris, Clements, Archie C. A., Craig, Scott B., Fuimaono, Saipale D. and Weinstein, Philip (2012) Leptospirosis in American Samoa 2010: epidemiology, environmental drivers, and the management of emergence. American Journal of Tropical Medicine and Hygiene, 86 2: 309-319. doi:10.4269/ajtmh.2012.11-0398


Author Lau, Colleen L.
Dobson, Annettee J.
Smythe, Lee D.
Fearnley, Emily J.
Skelly, Chris
Clements, Archie C. A.
Craig, Scott B.
Fuimaono, Saipale D.
Weinstein, Philip
Total Author Count Override 10
Title Leptospirosis in American Samoa 2010: epidemiology, environmental drivers, and the management of emergence
Journal name American Journal of Tropical Medicine and Hygiene   Check publisher's open access policy
ISSN 0002-9637
1476-1645
Publication date 2012-02
Sub-type Article (original research)
DOI 10.4269/ajtmh.2012.11-0398
Volume 86
Issue 2
Start page 309
End page 319
Total pages 11
Place of publication Deerfield, IL, United States
Publisher American Society of Tropical Medicine and Hygiene
Collection year 2013
Language eng
Abstract Leptospirosis has recently been reported as an emerging disease worldwide, and a seroprevalence study was undertaken in American Samoa to better understand the drivers of transmission. Antibodies indicative of previous exposure to leptospirosis were found in 15.5% of 807 participants, predominantly against three serovars that were not previously known to occur in American Samoa. Questionnaires and geographic information systems data were used to assess behavioral factors and environmental determinants of disease transmission, and logistic regression was used to identify factors associated with infection. Many statistically significant factors were consistent with previous studies, but we also showed a significant association with living at lower altitudes (odds ratio [OR] = 1.53, 95% confidence interval [CI]: 1.03–2.28), and having higher numbers of piggeries around the home (OR = 2.63, 95% CI: 1.52–4.40). Our findings support a multifaceted approach to combating the emergence of leptospirosis, including modification of individual behavior, but importantly also managing the evolving environmental drivers of risk.
Keyword Biodiversity
Infection
Outbreak
Diseases
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
ERA White List Items
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