Respiratory health effects of diesel particulate matter

Ristovski, Zoran D., Miljevic, Branka, Surawski, Nicholas C., Morawska, Lidia, Fong, Kwun M., Goh, Felicia and Yang, Ian A. (2012) Respiratory health effects of diesel particulate matter. Respirology, 17 2: 201-212. doi:10.1111/j.1440-1843.2011.02109.x


Author Ristovski, Zoran D.
Miljevic, Branka
Surawski, Nicholas C.
Morawska, Lidia
Fong, Kwun M.
Goh, Felicia
Yang, Ian A.
Title Respiratory health effects of diesel particulate matter
Journal name Respirology   Check publisher's open access policy
ISSN 1323-7799
1440-1843
Publication date 2012-02
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/j.1440-1843.2011.02109.x
Volume 17
Issue 2
Start page 201
End page 212
Total pages 12
Editor Ian Yang
Stephen Holgate
Place of publication Richmond, Vic., Australia
Publisher Wiley-Blackwell Publishing
Collection year 2013
Language eng
Abstract Particulate matter (PM) emissions involve a complex mixture of solid and liquid particles suspended in a gas, where it is noted that PM emissions from diesel engines are a major contributor to the ambient air pollution problem. While epidemiological studies have shown a link between increased ambient PM emissions and respiratory morbidity and mortality, studies of this design are not able to identify the PM constituents responsible for driving adverse respiratory health effects. This review explores in detail the physico-chemical properties of diesel PM (DPM) and identifies the constituents of this pollution source that are responsible for the development of respiratory disease. In particular, this review shows that the DPM surface area and adsorbed organic compounds play a significant role in manifesting chemical and cellular processes that if sustained can lead to the development of adverse respiratory health effects. The mechanisms of injury involved included inflammation, innate and acquired immunity, and oxidative stress. Understanding the mechanisms of lung injury from DPM will enhance efforts to protect at-risk individuals from the harmful respiratory effects of air pollutants.
Keyword Air pollution
Diesel exhaust
Health effect mechanism
Particulate matter
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes © 2011 The Authors. Respirology © 2011 Asian Pacific Society of Respirology. Invited Review Series: Air Pollution and Lung Health.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2013 Collection
School of Medicine Publications
 
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