Morphology of pelvic fin loss in a zebrafish strain (Danio rerio)

Don, Emily K., Hall, Thomas E., Currie, Peter D. and Cole, Nicholas J. (2011) Morphology of pelvic fin loss in a zebrafish strain (Danio rerio). Journal of Morphology, 272 5: 583-589. doi:10.1002/jmor.10938


Author Don, Emily K.
Hall, Thomas E.
Currie, Peter D.
Cole, Nicholas J.
Title Morphology of pelvic fin loss in a zebrafish strain (Danio rerio)
Journal name Journal of Morphology   Check publisher's open access policy
ISSN 0362-2525
Publication date 2011-05-01
Sub-type Article (original research)
DOI 10.1002/jmor.10938
Volume 272
Issue 5
Start page 583
End page 589
Total pages 7
Place of publication Hoboken, NJ, United States
Publisher John Wiley and Sons
Collection year 2012
Language eng
Formatted abstract
We describe the morphology of a zebrafish strain which lacks pelvic fins but no other abnormalities. This description is the first step of analyzing hindlimb loss in an established model organism. By combining light microscopy, bone and cartilage staining, scanning electron microscopy and histological sections we were able to comprehensively describe the morphology of the developing pelvic fins of a pelvic finless zebrafish in contrast with the developing pelvic fins of wild-type zebrafish. We have shown that although adult pelvic finless zebrafish completely lack pelvic fins, they do develop mesenchymal bulges in the pelvic regions at the pelvic fin development stage. Understanding the morphology and the subsequent genetic analysis of this fish will lead to important insights into both pelvic fin/hindlimb developmental mechanisms and the evolution of hindlimb loss. It is for this reason that we present a morphological analysis of pelvic fin development and loss in this genetically tractable model species.
Keyword Zebrafish
Limb
Fin
Development
Evolution
Threespine Sticklebacks
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Institute for Molecular Bioscience - Publications
 
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Created: Tue, 07 Feb 2012, 20:17:46 EST by Susan Allen on behalf of Institute for Molecular Bioscience