Dynamic changes in brain functional connectivity during concurrent dual-task performance

Cocchi, Luca, Zalesky, Andrew, Toepel, Ulrike, Whitford, Thomas J, De-Lucia, Marzia, Murray, Micah M. and Carter, Olivia (2011) Dynamic changes in brain functional connectivity during concurrent dual-task performance. Plos One, 6 11: e28301-1-e28301-9. doi:10.1371/journal.pone.0028301

Author Cocchi, Luca
Zalesky, Andrew
Toepel, Ulrike
Whitford, Thomas J
De-Lucia, Marzia
Murray, Micah M.
Carter, Olivia
Title Dynamic changes in brain functional connectivity during concurrent dual-task performance
Journal name Plos One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2011-11-29
Sub-type Article (original research)
DOI 10.1371/journal.pone.0028301
Open Access Status DOI
Volume 6
Issue 11
Start page e28301-1
End page e28301-9
Total pages 9
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Collection year 2012
Language eng
Abstract This study investigated the spatial, spectral, temporal and functional proprieties of functional brain connections involved in the concurrent execution of unrelated visual perception and working memory tasks. Electroencephalography data was analysed using a novel data-driven approach assessing source coherence at the whole-brain level. Three connections in the beta-band (18-24 Hz) and one in the gamma-band (30-40 Hz) were modulated by dual-task performance. Beta-coherence increased within two dorsofrontal-occipital connections in dual-task conditions compared to the single-task condition, with the highest coherence seen during low working memory load trials. In contrast, beta-coherence in a prefrontal-occipital functional connection and gamma-coherence in an inferior frontal-occipitoparietal connection was not affected by the addition of the second task and only showed elevated coherence under high working memory load. Analysis of coherence as a function of time suggested that the dorsofrontal-occipital beta-connections were relevant to working memory maintenance, while the prefrontal-occipital beta-connection and the inferior frontal-occipitoparietal gamma-connection were involved in top-down control of concurrent visual processing. The fact that increased coherence in the gamma-connection, from low to high working memory load, was negatively correlated with faster reaction time on the perception task supports this interpretation. Together, these results demonstrate that dual-task demands trigger non-linear changes in functional interactions between frontal-executive and occipitoparietal-perceptual cortices.
Keyword Working-Memory Load
Top-Down Control
Prefrontal Cortex
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2012 Collection
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 6 times in Scopus Article | Citations
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