Histocompatibility and osteogenic activity of Ti5Zr6Mo15Nb alloy with surface modification by porous TiO2 /HA coating

Yu, Sen, Yu, Zhentao, Han, Jianye, Niu, Jinlong, Wang, Gui and Dargusch, Matthew S. (2010) Histocompatibility and osteogenic activity of Ti5Zr6Mo15Nb alloy with surface modification by porous TiO2 /HA coating. Jinshu Rechuli [Heat Treatment of Metals], 35 9: 31-36.

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Author Yu, Sen
Yu, Zhentao
Han, Jianye
Niu, Jinlong
Wang, Gui
Dargusch, Matthew S.
Title Histocompatibility and osteogenic activity of Ti5Zr6Mo15Nb alloy with surface modification by porous TiO2 /HA coating
Journal name Jinshu Rechuli [Heat Treatment of Metals]
ISSN 0254-6051
Publication date 2010
Sub-type Article (original research)
Volume 35
Issue 9
Start page 31
End page 36
Total pages 6
Place of publication Beijing, China
Publisher Beijing Ji-Dian Yanjiusuo
Language chi
Abstract The porous TiO2/HA ( hydroxyapatite ) coating was prepared by micro arc oxidation method on the surface of novel near β biomedical titanium alloy Ti5Zr6Mo15Nb (TLE) in the electrolyte containing HA, after the above treatment the samples were submitted to active reactions in aqueous solution using sodium peroxydisulfate in oxalic acid solution. The phase composition and surface microtopography of the films we are investigated by XRD and SEM, and the histocompatibility in soft tissue and osteogenic activity of the coated TLE alloy were evaluated by animal test in vivo. The results show that the porous oxidation films are mainly composed of anatase, rutile and HA. The TLE alloy coated by porous TiO2 /HA coating exhibits good histocompatibility both in soft tissue and hard tissue, and it exhibits better osteogenic activity than the Ti5Zr6Mo15Nb alloy without surface modification.
Keyword TiO2/HA coating
Porous films
Histocompatibility
Osteogenic activity
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

 
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Created: Tue, 17 Jan 2012, 09:19:48 EST by Viviane Victoria Crosthwaite on behalf of Faculty Of Engineering, Architecture & Info Tech