Colonic mucosubmucosal elongated polyp: A clinicopathologic study of 13 cases and review of the literature

Alizart, Michelle Marie-Christine, Rosty, Christophe and Brown, Ian S. (2011) Colonic mucosubmucosal elongated polyp: A clinicopathologic study of 13 cases and review of the literature. American Journal of Surgical Pathology, 35 12: 1818-1822. doi:10.1097/PAS.0b013e31822c0688


Author Alizart, Michelle Marie-Christine
Rosty, Christophe
Brown, Ian S.
Title Colonic mucosubmucosal elongated polyp: A clinicopathologic study of 13 cases and review of the literature
Journal name American Journal of Surgical Pathology   Check publisher's open access policy
ISSN 0147-5185
1532-0979
Publication date 2011-12
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/PAS.0b013e31822c0688
Volume 35
Issue 12
Start page 1818
End page 1822
Total pages 5
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams and Wilkins
Collection year 2012
Language eng
Abstract Colonic mucosubmucosal elongated polyp (CMSEP)is a distinctive non-neoplastic colorectal polyp characterized by pedunculated, elongated shape and is composed mainly of expanded submucosa with a normal mucosal lining. Only a small number of these polyps have been reported, exclusively from Japan. We report the clinicopathologic characteristics of 13 CMSEPs occurring in 11 patients, mostly from European ancestry. Ten of these polyps were resected during colonoscopy, and 3 were diagnosed in a patient who underwent sigmoid resection for diverticular disease. Among patients who had undergone a colonoscopy, 4 had altered bowel habit, and 1 suffered from abdominal discomfort; the other 5 patients had routine screening colonoscopy. Eight polyps were located in the sigmoid colon, 3 in the right colon, 1 in the rectosigmoid junction, and 1 in the descending colon. Polyp size ranged from 10 to 150 mm. Histologically, CMSEPs were characterized by unremarkable large bowel mucosa and submucosal stalk containing dilated thick-walled veins running parallel to the long axis of the polyp. Mucosal inflammation or fibromuscular proliferation characteristic of mucosal prolapse was absent. The pathogenesis of CMSEP may involve mechanical traction of the mucosa and the superficial submucosa during peristalsis in a fragile area of the colon. Despite the occasional large size, CMSEP is a benign lesion seldom leading to clinical complications.
Keyword Colonic mucosubmucosal elongated polyp
CMSEP
Mucosal prolapse
Polypoid prolapsing mucosal fold
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2012 Collection
School of Medicine Publications
 
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