Cytochrome P450 drug interactions: are they clinically relevant?

Martin, Jennifer and Fay, Michael (2001) Cytochrome P450 drug interactions: are they clinically relevant?. Australian Prescriber, 24 1: 10-12.

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Author Martin, Jennifer
Fay, Michael
Title Cytochrome P450 drug interactions: are they clinically relevant?
Journal name Australian Prescriber   Check publisher's open access policy
ISSN 0312-8008
1839-3942
Publication date 2001-01
Sub-type Critical review of research, literature review, critical commentary
Open Access Status File (Publisher version)
Volume 24
Issue 1
Start page 10
End page 12
Total pages 3
Place of publication Deakin, ACT, Australia
Publisher National Prescribing Service
Language eng
Formatted abstract
The cytochrome P450 system is an evolutionary system to deal with the breakdown of endogenous and exogenous chemicals in the body. There is an increasing amount of interest in this area as new information is enabling us to understand why people metabolise drugs differently and why there is a spectrum of adverse effects in different people. Understanding the cytochrome P450 system also explains the mechanisms of some drug interactions, and enables us to predict which of these are likely to be relevant in clinical practice.
Keyword Pharmacokinetics
Drug metabolism
Warfarin
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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Created: Wed, 21 Dec 2011, 11:52:32 EST by Dr Jennifer Martin on behalf of Mater Clinical School