Acute severe non-traumatic muscle injury following reperfusion surgery for acute aortic occlusion: Case report

Ting, Joseph Y. and Dehdary, Arash (2011) Acute severe non-traumatic muscle injury following reperfusion surgery for acute aortic occlusion: Case report. International Journal of Emergency Medicine, 4 1: 20.1-20.4.

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Author Ting, Joseph Y.
Dehdary, Arash
Title Acute severe non-traumatic muscle injury following reperfusion surgery for acute aortic occlusion: Case report
Journal name International Journal of Emergency Medicine   Check publisher's open access policy
ISSN 1865-1380
Publication date 2011-12
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1186/1865-1380-4-20
Volume 4
Issue 1
Start page 20.1
End page 20.4
Total pages 4
Place of publication Heidelberg, Germany
Publisher SpringerOpen
Collection year 2012
Language eng
Abstract Acute aortic occlusion is a rare but catastrophic disease with a high mortality rate. Severe perioperative complications could result from revascularization of infarcted muscles. Muscle cell ischaemia and massive volume cell death lead to the release of myoglobin, potassium, and lactic acid, which could be fatal if not recognised or treated early. We highlight the life-threatening adverse effects resulting from bulk tissue infarction from nontraumatic causes such as aortic occlusion followed by the metabolic sequelae of reperfusion. This is similar to the pathophysiology of traumatic crush injuries and rhabdomyolysis. The case highlights the vigorous pre-emptive treatment of acidosis and hyperkalaemia required during surgical revascularisation to potentially avert adverse surgical outcomes in acute aortic obstruction.
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status Non-UQ
Additional Notes Article number 20

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Non HERDC
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Created: Wed, 14 Dec 2011, 09:01:23 EST by Matthew Lamb on behalf of School of Medicine