Association of left ventricular geometry with left atrial enlargement in patients with preserved ejection fraction

Patel, Dharmendrakumar A., Lavie, Carl J., Milani, Richard V., Gilliland, Yvonne, Shah, Sangeeta and Ventura, Hector O. (2012) Association of left ventricular geometry with left atrial enlargement in patients with preserved ejection fraction. Congestive Heart Failure, 18 1: 4-8. doi:10.1111/j.1751-7133.2011.00264.x


Author Patel, Dharmendrakumar A.
Lavie, Carl J.
Milani, Richard V.
Gilliland, Yvonne
Shah, Sangeeta
Ventura, Hector O.
Title Association of left ventricular geometry with left atrial enlargement in patients with preserved ejection fraction
Journal name Congestive Heart Failure   Check publisher's open access policy
ISSN 1527-5299
1751-7133
Publication date 2012-01
Year available 2011
Sub-type Article (original research)
DOI 10.1111/j.1751-7133.2011.00264.x
Volume 18
Issue 1
Start page 4
End page 8
Total pages 5
Place of publication Hoboken, NJ, United States
Publisher Le Jacq Communications
Collection year 2012
Language eng
Formatted abstract
Left ventricular (LV) hypertrophy (LVH) is a known independent determinant of left atrial (LA) size; however, there is controversy regarding whether the LV geometric patterns are associated with LA enlargement (LAE), a major indicator of diastolic heart failure. The authors evaluated 47,865 patients with preserved ejection fraction to determine the relationship of LV geometry on LAE as determined by LA volume index (LAVi) ≥29 mL/m2. Abnormal LV geometry was identified in 48% and LAE was indentified in 43% with associated higher prevalence of abnormal LV geometry (59% vs 41%, P<.0001). Both LV mass index and relative wall thickness (RWT) were independent determinants of LAE (P<.0001). LAVi and prevalence of LAE differ significantly by LV geometric patterns (P<.0001). In multivariate analysis, abnormal LV geometry patterns, especially eccentric and concentric LVH, were independently associated with LAE. In conclusion, LAE assessed as increased LAVi is strongly associated not only with LV mass index but also with RWT. Furthermore, LAE was independently associated with abnormalities in LV geometry.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online: 9 November 2011.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Medicine Publications
 
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Created: Tue, 13 Dec 2011, 08:25:00 EST by Matthew Lamb on behalf of School of Medicine