Environmental risk assessment of fluctuating diazinon concentrations in an urban and agricultural catchment using toxicokinetic-toxicodynamic modeling

Ashauer, Roman, Wittmer, Irene, Stamm, Christian and Escher, Beate I. (2011) Environmental risk assessment of fluctuating diazinon concentrations in an urban and agricultural catchment using toxicokinetic-toxicodynamic modeling. Environmental Science and Technology, 45 22: 9783-9792. doi:10.1021/es202413a


Author Ashauer, Roman
Wittmer, Irene
Stamm, Christian
Escher, Beate I.
Title Environmental risk assessment of fluctuating diazinon concentrations in an urban and agricultural catchment using toxicokinetic-toxicodynamic modeling
Journal name Environmental Science and Technology   Check publisher's open access policy
ISSN 0013-936X
1520-5851
Publication date 2011-11-15
Sub-type Article (original research)
DOI 10.1021/es202413a
Volume 45
Issue 22
Start page 9783
End page 9792
Total pages 10
Place of publication Washington, DC, United States
Publisher American Chemical Society
Collection year 2012
Language eng
Abstract Temporally resolved environmental risk assessment of fluctuating concentrations of micropollutants is presented. We separated the prediction of toxicity over time from the extrapolation from one to many species and from acute to sublethal effects. A toxicokinetic–toxicodynamic (TKTD) model predicted toxicity caused by fluctuating concentrations of diazinon, measured by time-resolved sampling over 108 days from three locations in a stream network, representing urban, agricultural and mixed land use. We calculated extrapolation factors to quantify variation in toxicity among species and effect types based on available toxicity data, while correcting for different test durations with the TKTD model. Sampling from the distribution of extrapolation factors and prediction of time-resolved toxicity with the TKTD model facilitated subsequent calculation of the risk of undesired toxic events. Approximately one-fifth of aquatic organisms were at risk and fluctuating concentrations were more toxic than their averages. Contribution of urban and agricultural sources of diazinon to the overall risk varied. Thus using fixed concentrations as water quality criteria appears overly simplistic because it ignores the temporal dimension of toxicity. However, the improved prediction of toxicity for fluctuating concentrations may be small compared to uncertainty due to limited diversity of toxicity data to base the extrapolation factors on.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
National Research Centre for Environmental Toxicology Publications
 
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