Confocal features of equivocal facial lesions on severely sun-damaged skin: Four case studies with dermatoscopic, confocal, and histopathologic correlation

Wurm, Elisabeth M.T., Curchin, Claudia E.S., Lambie, Duncan, Longo, Caterina, Pellacani, Giovanni and Soyer, H. Peter (2012) Confocal features of equivocal facial lesions on severely sun-damaged skin: Four case studies with dermatoscopic, confocal, and histopathologic correlation. Journal of the American Academy of Dermatology, 66 3: 463-473. doi:10.1016/j.jaad.2011.02.040

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Author Wurm, Elisabeth M.T.
Curchin, Claudia E.S.
Lambie, Duncan
Longo, Caterina
Pellacani, Giovanni
Soyer, H. Peter
Title Confocal features of equivocal facial lesions on severely sun-damaged skin: Four case studies with dermatoscopic, confocal, and histopathologic correlation
Journal name Journal of the American Academy of Dermatology   Check publisher's open access policy
ISSN 0190-9622
1097-6787
Publication date 2012-03
Year available 2011
Sub-type Article (original research)
DOI 10.1016/j.jaad.2011.02.040
Volume 66
Issue 3
Start page 463
End page 473
Total pages 11
Place of publication Philadelphia, PA, United States
Publisher Mosby
Collection year 2012
Language eng
Formatted abstract
Background:
Facial skin has a distinct histologic architecture and reveals specific dermatoscopic features. Diagnosis of lentigo maligna on the face is often challenging because of the overlap of clinical and morphologic features with other lesions.

Objectives:
We aim to show the value of reflectance confocal microscopy (RCM) as a noninvasive diagnostic tool for facial lesions and to increase knowledge of RCM morphologic features among the scientific community.

Methods:
We describe a series of 4 facial lesions on severely sun-damaged skin that was evaluated via RCM immediately after face-to-face examination, followed by shave biopsy for histopathological analysis.

Results:
Lesions included a lentigo maligna, a pigmented seborrheic keratosis, pigmented basal cell carcinoma, and a pigmented actinic keratosis. In the presented cases, RCM enabled an accurate diagnosis. Limitations: The study describes morphologic features on selected cases, but does not test accuracy of RCM criteria.

Conclusions:
RCM is a useful adjuvant for the accurate and precise diagnosis of equivocal facial lesions.
Keyword Basal cell carcinoma
Dermatoscopy; face
Histopathology
Lentigo maligna
Photodamaged skin
Pigmented actinic keratosis
Reflectance confocal microscopy
Seborrheic keratosis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online 5 October 2011

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Medicine Publications
 
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Created: Thu, 24 Nov 2011, 12:09:00 EST by Nicole Lin on behalf of Medicine - Princess Alexandra Hospital