Attract : A method for identifying core pathways that define cellular phenotypes

Mar, Jessica C., Matigian, Nicholas A., Quackenbush, John and Wells, Christine A. (2011) Attract : A method for identifying core pathways that define cellular phenotypes. PLoS One, 6 10 Article # e25445: e25445-1-e25445-6.


Author Mar, Jessica C.
Matigian, Nicholas A.
Quackenbush, John
Wells, Christine A.
Title Attract : A method for identifying core pathways that define cellular phenotypes
Journal name PLoS One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2011-10
Sub-type Article (original research)
DOI 10.1371/journal.pone.0025445
Volume 6
Issue 10 Article # e25445
Start page e25445-1
End page e25445-6
Total pages 7
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Collection year 2012
Language eng
Formatted abstract Attract is a knowledge-driven analytical approach for identifying and annotating the gene-sets that best discriminate between cell phenotypes. attract finds distinguishing patterns within pathways, decomposes pathways into meta-genes representative of these patterns, and then generates synexpression groups of highly correlated genes from the entire transcriptome dataset. attract can be applied to a wide range of biological systems and is freely available as a Bioconductor package and has been incorporated into the MeV software system.
Keyword Gene Set Enrichment
Coexpression Network Analysis
Expression Profiles
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
Australian Institute for Bioengineering and Nanotechnology Publications
 
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