Patient characteristics from a regional multicenter database of acute decompensated heart failure in Asia Pacific (ADHERE International-Asia Pacific)

Atherton, John J., Hayward, Christopher S., Wan Ahmad, Wan Azman, Kwok, Bernard, Jorge, Jesus, Hernandez, Adrian F., Liang, Li, Kociol, Robb D. and Krum, Henry (2012) Patient characteristics from a regional multicenter database of acute decompensated heart failure in Asia Pacific (ADHERE International-Asia Pacific). Journal of Cardiac Failure, 18 1: 82-88. doi:10.1016/j.cardfail.2011.09.003


Author Atherton, John J.
Hayward, Christopher S.
Wan Ahmad, Wan Azman
Kwok, Bernard
Jorge, Jesus
Hernandez, Adrian F.
Liang, Li
Kociol, Robb D.
Krum, Henry
Title Patient characteristics from a regional multicenter database of acute decompensated heart failure in Asia Pacific (ADHERE International-Asia Pacific)
Journal name Journal of Cardiac Failure   Check publisher's open access policy
ISSN 1071-9164
1532-8414
Publication date 2012-01
Year available 2011
Sub-type Article (original research)
DOI 10.1016/j.cardfail.2011.09.003
Volume 18
Issue 1
Start page 82
End page 88
Total pages 7
Place of publication Philadelphia, PA, United States
Publisher Churchill Livingstone
Collection year 2012
Language eng
Formatted abstract
Background:
Heart failure (HF) is a leading cause of hospitalization. Although a number of multicenter international HF hospital registries have been published, there are limited data for the Asia Pacific region.

Methods:
ADHERE (ie, Acute Decompensated Heart Failure Registry) International–Asia Pacific is an electronic web-based observational database of 10,171 patients hospitalized with a principal diagnosis of HF from 8 Asia-Pacific countries between January 2006 and December 2008.

Results:
The median age (67 years) varied by more than 2 decades across the region. Fifty-seven percent of patients were male. Ninety percent of patients were Asian and 8.4% were white. Dyspnea was the presenting symptom in 95%, with 80% having documented rales. During the index hospitalization, left ventricular function was assessed in 50%, and intravenous therapies included diuretics (85%), vasodilators (14%), and positive inotropes (15%). In-hospital mortality was 4.8%. Discharge medications included angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers (63%), β-blockers (41%), and aldosterone antagonists (31%).

Conclusions:
Compared with other multicenter registries, patients hospitalized with acute HF in the Asia Pacific region tend to present with more severe clinical symptoms and signs and are younger, especially in countries at an earlier stage in their epidemiological transition. Echocardiography and disease-modifying medications are used less often, highlighting potential opportunities to improve outcomes.
Keyword Heart failure
Registry
Quality indicators
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes FOR THE ADHERE INTERNATIONAL - ASIA PACIFIC SCIENTIFIC ADVISORY COMMITTEE. Available online 8 October 2011.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Medicine Publications
 
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Created: Fri, 28 Oct 2011, 10:53:39 EST by Matthew Lamb on behalf of School of Medicine