A case for whole-parasite malaria vaccines

Wykes, Michelle and Good, Michael F. (2007) A case for whole-parasite malaria vaccines. International Journal for Parasitology, 37 7: 705-712.


Author Wykes, Michelle
Good, Michael F.
Title A case for whole-parasite malaria vaccines
Journal name International Journal for Parasitology   Check publisher's open access policy
ISSN 0020-7519
1879-0135
Publication date 2007-06
Sub-type Article (original research)
DOI 10.1016/j.ijpara.2007.02.007
Volume 37
Issue 7
Start page 705
End page 712
Total pages 8
Place of publication Oxford, United Kingdom
Publisher Elsevier
Language eng
Abstract Malaria causes morbidity in 300–500 million people each year and claims 2–3 millions lives annually, mostly children in sub-Saharan Africa. In 1983, the cloning of malaria antigens offered great promise for developing a viable subunit vaccine. However, an efficacious human vaccine is still not available. Immunological studies on how the host’s immune system interacts with the parasite and studies on the pathogenic aspect of Plasmodium have found that several factors can impede protection by current vaccines. These findings suggest a novel approach needs to be considered.
Keyword Malaria
Vaccines
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: ERA 2012 Admin Only
School of Population Health Publications
 
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Created: Tue, 25 Oct 2011, 13:14:56 EST by Geraldine Fitzgerald on behalf of School of Population Health