Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines

Chen, Nanhua, Wilson, Danny W., Pasay, Cielo, Bell, David, Martin, Laura B., Kyle, Dennis and Cheng, Qin (2005) Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines. Antimicrobial Agents & Chemotherapy, 49 5: 2102-2105. doi:10.1128/AAC.49.5.2102-2105.2005

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Author Chen, Nanhua
Wilson, Danny W.
Pasay, Cielo
Bell, David
Martin, Laura B.
Kyle, Dennis
Cheng, Qin
Title Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines
Formatted title
Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines
Journal name Antimicrobial Agents & Chemotherapy   Check publisher's open access policy
ISSN 0066-4804
1098-6596
Publication date 2005-05
Sub-type Article (original research)
DOI 10.1128/AAC.49.5.2102-2105.2005
Open Access Status File (Publisher version)
Volume 49
Issue 5
Start page 2102
End page 2105
Total pages 4
Place of publication Washington, DC, United States
Publisher American Society for Microbiology
Language eng
Formatted abstract
The pfcrt allelic type and adjacent microsatellite marker type were determined for 82 Plasmodium falciparum isolates from the Philippines. Mutant pfcrt allelic types P1a and P2a/P2b were dominant in different locations. Microsatellite analysis revealed that P2a/P2b evolved independently in the Philippines, while P1a shared common ancestry with Papua New Guinea chloroquine-resistant parasites.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: ERA 2012 Admin Only
School of Public Health Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 34 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 25 Oct 2011, 10:13:18 EST by Geraldine Fitzgerald on behalf of School of Public Health