Hyperbranched polymers for molecular imaging: Designing polymers for parahydrogen induced polarisation (PHIP)

Munnemann, Kerstin, Kolzer, Michael, Blakey, Idriss, Whittaker, Andrew K. and Thurecht, Kristofer J. (2012) Hyperbranched polymers for molecular imaging: Designing polymers for parahydrogen induced polarisation (PHIP). Chemical Communications, 48 10: 1583-1585. doi:10.1039/c1cc16077j


Author Munnemann, Kerstin
Kolzer, Michael
Blakey, Idriss
Whittaker, Andrew K.
Thurecht, Kristofer J.
Title Hyperbranched polymers for molecular imaging: Designing polymers for parahydrogen induced polarisation (PHIP)
Journal name Chemical Communications   Check publisher's open access policy
ISSN 1359-7345
1364-548X
Publication date 2012-02-01
Year available 2011
Sub-type Article (original research)
DOI 10.1039/c1cc16077j
Volume 48
Issue 10
Start page 1583
End page 1585
Total pages 3
Place of publication Cambridge, United Kingdom
Publisher Royal Society of Chemistry
Collection year 2012
Language eng
Abstract The first hyperpolarisation of polymers using parahydrogen induced polarisation (PHIP) is reported by hydrogenation of terminal alkyne groups in a biocompatible hyperbranched polymer. Signal enhancements of 1500-fold could be obtained depending on the structure of the polymer, thus opening new potential avenues for polymeric molecular imaging.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes First published on the web 17 Oct 2011

 
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Created: Mon, 24 Oct 2011, 12:09:34 EST by Sandrine Ducrot on behalf of Centre for Advanced Imaging