Viral metagenomics: From fish slime to the world

Willner, Dana, Desnues, Christelle and Rohwer, Forest (2011). Viral metagenomics: From fish slime to the world. In Robert W. Li (Ed.), Metagenomics and its applications in agriculture, biomedicine, and environmental studies (pp. 337-366) Hauppauge, NY, U.S.A.: Nova Scientific Publishers.

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Name Description MIMEType Size Downloads
Author Willner, Dana
Desnues, Christelle
Rohwer, Forest
Title of chapter Viral metagenomics: From fish slime to the world
Title of book Metagenomics and its applications in agriculture, biomedicine, and environmental studies
Place of Publication Hauppauge, NY, U.S.A.
Publisher Nova Scientific Publishers
Publication Year 2011
Sub-type Chapter in textbook
Series Genetics: Research and Issues
ISBN 9781616686826
1616686820
9781617287312
1617287318
Editor Robert W. Li
Chapter number 17
Start page 337
End page 366
Total pages 30
Total chapters 21
Collection year 2012
Language eng
Formatted Abstract/Summary Viruses comprise the majority of the uncharacterized genomic diversity on the
planet. Phage are especially diverse, with estimates of 100 million phage species on
Earth. Culturing-based approaches to study this diversity are not feasible, due to the scale of the problem and the inability to culture viruses and/or their hosts. Culture-independent methods such as 16S rDNA analysis, which have been so successful for changing our view of microbial diversity, are not applicable to viruses because they do not share signature genes. Shotgun metagenomics was first developed to escape these limitations. We will review how metagenomic methods have been used to survey viral communities in most of the world's major biomes, focusing on known agricultural applications. Additionally, a case study of viruses associated with healthy and morbid aquaculture fish will be used to review current experimental and bioinformatic approaches to viral metagenomics in aquaculture.
Q-Index Code BX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Book Chapter
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School of Chemistry and Molecular Biosciences
 
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Created: Thu, 20 Oct 2011, 09:21:46 EST by Dana Willner on behalf of School of Chemistry & Molecular Biosciences