The epidemiology of Koala retrovirus

Simmons, Greg, Young, Paul, McKee, Jeff, Meers, Joanne and Mizuno, Tetsuo (2011) The epidemiology of Koala retrovirus. Juiekigaku Zasshi, 15 . doi:10.2743/jve.15.1

Author Simmons, Greg
Young, Paul
McKee, Jeff
Meers, Joanne
Mizuno, Tetsuo
Title The epidemiology of Koala retrovirus
Formatted title
The epidemiology of Koala retrovirus
Journal name Juiekigaku Zasshi   Check publisher's open access policy
Translated journal name Journal of Veterinary Epidemiology
Language of Journal Name jpn
ISSN 1343-2583
Publication date 2011-07
Sub-type Article (original research)
DOI 10.2743/jve.15.1
Volume 15
Total pages 9
Place of publication Tsukuba, Japan
Publisher The Japan Society of Veterinary Epidemiology
Collection year 2012
Language jpn
Formatted abstract
A novel Gammaretrovirus, named Koala retrovirus (KoRV) was identified in koalas in 2000. Subsequent testing has shown that KoRV appears to be widespread throughout the wild koala population in Australia. KoRV is apparently unique in that it is the only known example of an exogenous retrovirus which is actively undergoing the process of endogenisation. While there is currently little direct evidence that KoRV causes overt disease in koalas, it is possible or even likely that KoRV infection plays a significant role in the pathogenesis of various neoplasms and a variety of immunosuppressive disorders which are commonly diagnosed in koalas. It appears that KoRV may have arisen through the cross species transmission of a closely related retrovirus in a native Australian rodent, the grassland melomys. Both of these viruses are closely related to a third retrovirus, Gibbon ape leukaemia virus (GALV). GALV was first isolated in the late 1960's from captive gibbons in Thailand that were suffering from leukaemia. To date, the source of GALV remains unknown.
Keyword Koala
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Chemistry and Molecular Biosciences
School of Veterinary Science Publications
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Created: Thu, 20 Oct 2011, 09:14:14 EST by Mr Gregory Simmons on behalf of School of Veterinary Science