Gender differences in metabolic syndrome - A key research issue

Iyer, Abishek, Kauter, Kathleen and Brown, Lindsay (2011) Gender differences in metabolic syndrome - A key research issue. Endocrine, Metabolic and Immune Disorders - Drug Targets, 11 3: 182-188. doi:10.2174/187153011796429808

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Author Iyer, Abishek
Kauter, Kathleen
Brown, Lindsay
Title Gender differences in metabolic syndrome - A key research issue
Journal name Endocrine, Metabolic and Immune Disorders - Drug Targets   Check publisher's open access policy
ISSN 1871-5303
2212-3873
Publication date 2011-09
Sub-type Article (original research)
DOI 10.2174/187153011796429808
Volume 11
Issue 3
Start page 182
End page 188
Total pages 7
Place of publication Bussum, Netherlands
Publisher Bentham Science Publishers
Collection year 2012
Language eng
Abstract Metabolic syndrome as a clustering of risk factors for diabetes and cardiovascular disease affects both men and women, but with important gender differences. Animal models have been used to understand disease progression and define therapeutic options, but most pre-clinical research on metabolic syndrome is undertaken in males. This opinion piece discusses the differences in male and female physiology that may influence both the development and the responses to pharmacological interventions of metabolic disorders, especially obesity. An appreciation of gender differences should improve the design and usefulness of biomedical experimental research to allow the development of relevant genderbased treatment options for chronic diseases including obesity, metabolic and cardiovascular diseases.
Keyword Female bias
Metabolic syndrome
Inflammation
Cardiovascular disease
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Biomedical Sciences Publications
 
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Created: Mon, 17 Oct 2011, 15:11:49 EST by Bacsweet Kaur on behalf of School of Biomedical Sciences