Preparation and osteoinduction of active micro-arc oxidation films on Ti-3Zr-2Sn-3Mo-25Nb alloy

Yu, Sen, Yu, Zhen-tao, Wang, Gui, Han, Jian-ye, Ma, Xi-qun and Dargusch, Matthew S. (2011) Preparation and osteoinduction of active micro-arc oxidation films on Ti-3Zr-2Sn-3Mo-25Nb alloy. Transactions of Nonferrous Metals Society of China, 21 3: 573-580. doi:10.1016/S1003-6326(11)60753-X


Author Yu, Sen
Yu, Zhen-tao
Wang, Gui
Han, Jian-ye
Ma, Xi-qun
Dargusch, Matthew S.
Title Preparation and osteoinduction of active micro-arc oxidation films on Ti-3Zr-2Sn-3Mo-25Nb alloy
Journal name Transactions of Nonferrous Metals Society of China   Check publisher's open access policy
ISSN 1003-6326
1004-0609
2210-3384
Publication date 2011-03
Sub-type Article (original research)
DOI 10.1016/S1003-6326(11)60753-X
Volume 21
Issue 3
Start page 573
End page 580
Total pages 8
Place of publication Changsha, China
Publisher Nonferrous Metals Society of China
Collection year 2012
Language eng
Formatted abstract
A layer of porous film containing Ca and P was prepared by the micro-arc oxidation method on the surface of a novel near β biomedical Ti-3Zr-2Sn-3Mo-25Nb alloy, and then NH2 active group was introduced to the films by activation treatment. The phase composition, surface micro-topography and elemental characteristics of the micro-arc oxidation films were investigated with XRD, SEM, EDS and XPS, and the osteoinduction of the micro-arc oxidation films was tested using the simulated body fluid immersion, the in-vitro osteoblast cultivation test and animal experiment. The results show that the oxide layer is a kind of porous ceramic intermixture and contains Ca and P. The films in the simulated body fluid can induce apatite formation, resulting in excellent bioactivity. The cell test discovers that osteoblasts can grow well on the surface of micro-arc oxidation films. And the Ti-3Zr-2Sn-3Mo-25Nb biomedical alloy coated with active porous calcium-phosphate films shows better osteoinduction in vivo.
Keyword Beta Titanium alloy
Ti-3Zr-2Sn-3Mo-25Nb alloy
Osteoinduction
Micro-arc oxidation
Surface modification
β Titanium alloy
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mechanical & Mining Engineering Publications
Official 2012 Collection
 
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Created: Mon, 17 Oct 2011, 11:43:46 EST by Viviane Victoria Crosthwaite on behalf of School of Mechanical and Mining Engineering