Masked hypertension is "unmasked" by low-intensity exercise blood pressure

Schultz, Martin G., Hare, James L., Marwick, Thomas H., Stowasser, Michael and Sharman, James E. (2011) Masked hypertension is "unmasked" by low-intensity exercise blood pressure. Blood Pressure, 20 5: 284-289. doi:10.3109/08037051.2011.566251


Author Schultz, Martin G.
Hare, James L.
Marwick, Thomas H.
Stowasser, Michael
Sharman, James E.
Title Masked hypertension is "unmasked" by low-intensity exercise blood pressure
Journal name Blood Pressure   Check publisher's open access policy
ISSN 0803-7051
1651-1999
Publication date 2011-10
Sub-type Article (original research)
DOI 10.3109/08037051.2011.566251
Volume 20
Issue 5
Start page 284
End page 289
Total pages 6
Place of publication London, United Kingdom
Publisher Informa Healthcare
Collection year 2012
Language eng
Formatted abstract
Purpose. Masked hypertension (MH) independently predicts mortality but cannot be diagnosed from clinic blood pressure (BP) taken under resting conditions. We sought to determine if MH could be identified from BP taken during a single bout of low-intensity exercise. Methods. BP was recorded at rest and during brief low-level cycling exercise (60–70% of age-predicted maximal heart rate) in 75 untreated subjects with a hypertensive response to exercise (aged 54 ± 9 years). All subjects underwent 24-h ambulatory BP monitoring (ABPM) and MH was defined as clinic BP < 140/90 mmHg and ABPM BP ≥ 130/80 mmHg. Results. There were 42 (56%) patients with MH, and at rest systolic (SBP) was higher in subjects with MH compared with those without MH (127 ± 9 vs 120 ± 9 mmHg; p < 0.05). During exercise, MH subjects had significantly higher SBP (188 ± 22 vs 168 ± 15 mmHg; p < 0.05), with a greater change from baseline (61 ± 21 vs 48 ± 15 mmHg; p < 0.05). Low-level exercise SBP was independently associated with MH, and if ≥175 mmHg, identified MH with 74% sensitivity and 67% specificity (p < 0.001). Conclusion. MH can be identified in untreated individuals from low-intensity exercise SBP. Further research on the diagnostic value of BP during early phases of exercise stress testing is needed.
Keyword Blood pressure
Exercise
Hypertension
Masked hypertension
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Medicine Publications
 
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