Prediction of fat-free mass and percentage body fat in neonates using bioelectrical impedance analysis and anthropometric measures: Validation against the PEA POD

Lingwood, Barbara E., Storm van Leeuwen, Anne-Martine, Carberry, Angela E., Fitzgerald, Erin C., Callaway, Leonie K., Colditz, Paul B. and Ward, Leigh C. (2012) Prediction of fat-free mass and percentage body fat in neonates using bioelectrical impedance analysis and anthropometric measures: Validation against the PEA POD. The British Journal of Nutrition, 107 10: 1545-1552. doi:10.1017/S0007114511004624


Author Lingwood, Barbara E.
Storm van Leeuwen, Anne-Martine
Carberry, Angela E.
Fitzgerald, Erin C.
Callaway, Leonie K.
Colditz, Paul B.
Ward, Leigh C.
Title Prediction of fat-free mass and percentage body fat in neonates using bioelectrical impedance analysis and anthropometric measures: Validation against the PEA POD
Journal name The British Journal of Nutrition   Check publisher's open access policy
ISSN 1475-2662
0007-1145
Publication date 2012-05
Year available 2011
Sub-type Article (original research)
DOI 10.1017/S0007114511004624
Volume 107
Issue 10
Start page 1545
End page 1552
Total pages 8
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Collection year 2012
Language eng
Formatted abstract
Accurate assessment of neonatal body composition is essential to studies investigating neonatal nutrition or developmental origins of obesity. Bioelectrical impedance analysis or bioimpedance analysis is inexpensive, non-invasive and portable, and is widely used in adults for the assessment of body composition. There are currently no prediction algorithms using bioimpedance analysis in neonates that have been directly validated against measurements of fat-free mass (FFM). The aim of the study was to evaluate the use of bioimpedance analysis for the estimation of FFM and percentage of body fat over the first 4 months of life in healthy infants born at term, and to compare these with estimations based on anthropometric measurements (weight and length) and with skinfolds. The present study was an observational study in seventy-seven infants. Body fat content of infants was assessed at birth, 6 weeks, 3 and 4·5 months of age by air displacement plethysmography, using the PEA POD body composition system. Bioimpedance analysis was performed at the same time and the data were used to develop and test prediction equations for FFM. The combination of weight+sex+length predicted FFM, with a bias of <100g and limits of agreement of 6–13%. Before 3 months of age, bioimpedance analysis did not improve the prediction of FFM or body fat. At 3 and 4·5 months, the inclusion of impedance in prediction algorithms resulted in small improvements in prediction of FFM, reducing the bias to <50g and limits of agreement to <9%. Skinfold measurements performed poorly at all ages.
Keyword Neonatal body composition assessment
Prediction equations
Bioelectrical impedance
Anthropometrics
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online: 15 September 2011.

 
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Created: Thu, 13 Oct 2011, 11:59:46 EST by Professor Paul Colditz on behalf of Obstetrics & Gynaecology - RBWH