Botulinum neurotoxin for failed tracheoesophageal speech: phonatory and functional outcomes

Lawson, Nadine R., Ward, Elizabeth C., Duncan, Natalie J., Baxter, Malcolm, Sizeland, Andrew and Hughes, Andrew J. (2011) Botulinum neurotoxin for failed tracheoesophageal speech: phonatory and functional outcomes. Journal of Medical Speech Language Pathology, 19 3: 1-11.

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Name Description MIMEType Size Downloads
Author Lawson, Nadine R.
Ward, Elizabeth C.
Duncan, Natalie J.
Baxter, Malcolm
Sizeland, Andrew
Hughes, Andrew J.
Title Botulinum neurotoxin for failed tracheoesophageal speech: phonatory and functional outcomes
Journal name Journal of Medical Speech Language Pathology   Check publisher's open access policy
ISSN 1065-1438
Publication date 2011-09-01
Sub-type Article (original research)
Volume 19
Issue 3
Start page 1
End page 11
Total pages 11
Place of publication Florence, KY, United States
Publisher Delmar Cengage Learning
Collection year 2012
Language eng
Abstract Priorresearch supports theuseofbotulinumtoxintoimprove phonatory durationforlaryngectomy patients with failed tracheoesophageal speech (TES) caused by hypertonicity or spasm ofthe pharyngoesophageal (PE) segment. However, few studies to date have examined its impact on connected speech, and no studies have explored whether treatment has a positive impact on psychosocial function. In the current study, the effects of botulinum toxin injection as a voice restoration technique were examined in seven laryngectomy patients with failed TES as a result of PE segment hypertonicity with or without spasm. Preinjection and at five times postinjection (2 weeks; 3, 6, 12, and 24 months) participants underwent perceptual assessments of phonatory duration, phonatory fluency in conversation, and completed the Voice Handicap Index (VHI), a voice-related functional impact measure. Results revealed improvements in phonation duration, phonation duration per breath, and VHI score for all participants and improvements in conversational voice fluency for four participants post injection. Three participants experienced botulinum toxin failure and required reinjection during the study period. Botulinum toxin injection into the hypertonic PE segment is an effective technique to help restore phonatory function, improve phonation in connected speech, and reduce the negative impact ofimpaired voicing on everyday life for individuals with nonfluent TES.
Keyword Botulinum toxin
Voice Handicap Index
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Health and Rehabilitation Sciences Publications
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Created: Thu, 13 Oct 2011, 10:51:41 EST by Professor Elizabeth Ward on behalf of School of Health & Rehabilitation Sciences