Advances in structural and molecular neuroimaging in Alzheimer's disease

Ellis, Kathryn A., Rowe, Christopher C., Szoeke, Cassandra E. I., Villemagne, Victor L., Ames, David, Chetelat, Gael, Martins, Ralph N., Masters, Colin L., Fripp, Jurgen, Acosta, Oscar, Raniga, Parnesh, Bourgeat, Pierrick T. and Salvado, Olivier (2011) Advances in structural and molecular neuroimaging in Alzheimer's disease. Medical Journal of Australia, 194 4: S20-S23.

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Author Ellis, Kathryn A.
Rowe, Christopher C.
Szoeke, Cassandra E. I.
Villemagne, Victor L.
Ames, David
Chetelat, Gael
Martins, Ralph N.
Masters, Colin L.
Fripp, Jurgen
Acosta, Oscar
Raniga, Parnesh
Bourgeat, Pierrick T.
Salvado, Olivier
Title Advances in structural and molecular neuroimaging in Alzheimer's disease
Journal name Medical Journal of Australia   Check publisher's open access policy
ISSN 0025-729X
Publication date 2011-02
Sub-type Article (original research)
Volume 194
Issue 4
Start page S20
End page S23
Total pages 4
Place of publication Strawberry Hills, NSW, Australia
Publisher Australasian Medical Publishing
Collection year 2012
Language eng
Formatted abstract
• Longer life expectancies lead to increases in the prevalence of age-associated illnesses. The number of Australians with dementia is predicted to rise, from 234 000 in 2009 to over 1 million by 2050, as a result of the increased prevalence of
Alzheimer’s disease (AD), the leading cause of dementia in the elderly.
• Early diagnosis of AD will become more important as diseasemodifying therapies emerge within the next decade.
• Advances in molecular neuroimaging with amyloid-β-specific
radioligands for positron emission tomography, aided by magnetic resonance imaging techniques, allow detection of AD years before symptoms of dementia develop.
• Longitudinal prospective studies, such as the Australian Imaging Biomarkers and Lifestyle (AIBL) study of ageing, will determine the sensitivity and specificity of these analysis techniques for diagnosing AD and predicting cognitive decline.
Keyword Mild Cognitive Impairment
Beta-Amyloid Burden
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status Non-UQ

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