Fast acquisition methods in multidimensional NMR

Mobli, Mehdi, Hoch, Jeffrey C. and King, Glenn F. (2011). Fast acquisition methods in multidimensional NMR. In Andrew J. Dingley and Steven M. Pascal (Ed.), Biomolecular NMR spectroscopy (pp. 305-337) Amsterdam , Netherlands: IOS Press. doi:10.3233/978-1-60750-695-9-305

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Author Mobli, Mehdi
Hoch, Jeffrey C.
King, Glenn F.
Title of chapter Fast acquisition methods in multidimensional NMR
Title of book Biomolecular NMR spectroscopy
Place of Publication Amsterdam , Netherlands
Publisher IOS Press
Publication Year 2011
Sub-type Research book chapter (original research)
DOI 10.3233/978-1-60750-695-9-305
Series Advances in Biomedical Spectroscopy
ISBN 9781607506942; 607506947; 1875-0656
ISSN 1875-0656
Editor Andrew J. Dingley
Steven M. Pascal
Volume number 3
Chapter number 15
Start page 305
End page 337
Total pages 33
Total chapters 21
Collection year 2012
Language eng
Abstract/Summary The advent of isotope labeling strategies for macromolecules has enabled the application of multidimensional heteronuclear NMR experiments to biomolecular systems of unprecedented size and complexity. The improved signal dispersion afforded by multiple dimensions; however, comes at a price: each added dimension exponentially increases the required NMR data acquisition time if the conventional approach of Fourier Transform NMR is employed. Efforts to overcome this time barrier have been given additional impetus due to technological advances such as the advent of cryogenically cooled probes, increased strength of high-field magnets, and improvements in computation. In this chapter we review the most successful methods for accelerating NMR data acquisition, highlighting relationships among the methods as well as their respective strengths and weaknesses. Our aim is to provide a practical reference guide for researchers to better understand this rapidly growing field and help identify the approach best suited to a particular problem. [from publisher's website]
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Fri, 07 Oct 2011, 14:25:38 EST by Professor Glenn King on behalf of School of Chemistry & Molecular Biosciences