Hypoxic conditions during kidney development disrupt nephron formation

Wilkinson, L. J., Chiu, H., Ju, A., Rumballe, B., Georgas, K., Moritz, K. M. and Little, M. H. (2011). Hypoxic conditions during kidney development disrupt nephron formation. In: 47th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology. ANZSN 2011: 47th Annual Scientific Meeting Australian and New Zealand Society of Nephrology, Adelaide, SA, Australia, (52-52). 17-21 September 2011. doi:10.1111/j.1440-1797.2011.01491.x


Author Wilkinson, L. J.
Chiu, H.
Ju, A.
Rumballe, B.
Georgas, K.
Moritz, K. M.
Little, M. H.
Title of paper Hypoxic conditions during kidney development disrupt nephron formation
Conference name ANZSN 2011: 47th Annual Scientific Meeting Australian and New Zealand Society of Nephrology
Conference location Adelaide, SA, Australia
Conference dates 17-21 September 2011
Convener Australian and New Zealand Society of Nephrology
Proceedings title 47th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology   Check publisher's open access policy
Journal name Nephrology   Check publisher's open access policy
Place of Publication Richmond, VIC, Australia
Publisher Wiley-Blackwell Publishing Asia
Publication Year 2011
Sub-type Published abstract
DOI 10.1111/j.1440-1797.2011.01491.x
ISSN 1320-5358
1440-1797
Volume 16
Issue Supp. s1
Start page 52
End page 52
Total pages 1
Collection year 2012
Language eng
Formatted Abstract/Summary
Aim: To determine the effect of hypoxia on nephron endowment.

Conclusions: Activation of the hypoxic response pathway results in a block in the mesenchyme to epithelial transition required for nephron formation. This may be due to ER stress associated degradation of key signaling molecules such as Wnt9b.
Q-Index Code EX
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Publication date: September 2011. Presented during the Session "Oral Mini-Posters 5: Experimental Immunology and Developmental Biology" as Poster #109.

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in Thomson Reuters Web of Science Article
Google Scholar Search Google Scholar
Created: Sun, 02 Oct 2011, 00:05:15 EST by System User on behalf of Institute for Molecular Bioscience