Finally, how histone deacetylase inhibitors disrupt mitosis!

Gabrielli, Brian, Chia, KeeMing and Warrener, Robyn (2011) Finally, how histone deacetylase inhibitors disrupt mitosis!. Cell Cycle, 10 16: 2658-2661. doi:10.4161/cc.10.16.16953


Author Gabrielli, Brian
Chia, KeeMing
Warrener, Robyn
Title Finally, how histone deacetylase inhibitors disrupt mitosis!
Journal name Cell Cycle   Check publisher's open access policy
ISSN 1538-4101
Publication date 2011-08
Sub-type Article (original research)
DOI 10.4161/cc.10.16.16953
Volume 10
Issue 16
Start page 2658
End page 2661
Total pages 4
Place of publication United States
Publisher Landes Bioscience
Collection year 2012
Language eng
Abstract The disruption of normal mitosis by histone deacetylase inhibitors is a significant contributor to the anti-cancer effects of these drugs. However, the mechanism by which these drugs affect mitosis is poorly understood. A number of recent papers have now thrown considerable light onto how these drugs elicit this very distinctive cell cycle disruption.
Keyword HDACi
Haspin
chromosomal passenger complex
Sister-Chromatid Separation
Aurora-B
Mitotic Spindle
Lysine 9
H3
Checkpoint
Kinase
Cytotoxicity
Acetylation
Methylation
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
UQ Diamantina Institute Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
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