Skin surface topography grading is a valid measure of skin photoaging

Battistutta, Diana, Pandeya, Nirmala, Strutton, Geoffrey M., Fourtanier, Anny, Tison, Sylvie and Green, Ade` le C. (2006) Skin surface topography grading is a valid measure of skin photoaging. Photodermatology Photoimmunology & Photomedicine, 22 1: 39-45. doi:10.1111/j.1600-0781.2006.00194.x


Author Battistutta, Diana
Pandeya, Nirmala
Strutton, Geoffrey M.
Fourtanier, Anny
Tison, Sylvie
Green, Ade` le C.
Title Skin surface topography grading is a valid measure of skin photoaging
Journal name Photodermatology Photoimmunology & Photomedicine   Check publisher's open access policy
ISSN 0905-4383
Publication date 2006-02
Sub-type Article (original research)
DOI 10.1111/j.1600-0781.2006.00194.x
Volume 22
Issue 1
Start page 39
End page 45
Total pages 7
Place of publication United States
Publisher Wiley-Blackwell Publishing, Inc.
Language eng
Formatted abstract
Background:
The technique of grading the surface topography of sun-exposed skin using silicone impressions of the skin surface is a simple, non-invasive method for measuring skin damage because of sun exposure, but it has never been validated in a community setting.

Objective:

To investigate the repeatability and validity of using standardly-graded skin impressions as a means of assessing skin Photoaging. Patients/Methods: A random sample of 195 adults aged 18-79 years and living in Nambour, Australia (latitude, 26° South) had a silicone impression taken of the back of the left hand and a 2 mm punch biopsy of the skin at the same site. Silicone impressions were graded twice independently and histological photoaging was determined by two pathologists.

Results:
Grading of silicone impressions of skin surface topography was highly repeatable (weighted κ>0.8). Compared with those with low skin impression grades (least degeneration), people with high grades were three times more likely to show a high degree of dermal elastosis on skin histology (odds ratio 3.1, 95% confidence interval 1.6, 5.7) after adjusting for age, sex, skin colour, tanning ability, occupational exposure, smoking and height-adjusted weight. Other photoaging changes in the stratum corneum and dermis were also strongly correlated with high grades of damage on skin impressions.

Conclusion:
Grading silicone impressions of skin surface topography is a highly reliable and a valid measure of photoaging and enables prediction of dermal elastosis in a population setting.
Keyword Dermal elastosis
Photoaging
Skin surface topography
Ultraviolet radiation
Sun Exposure
Aged Skin
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: ERA 2012 Admin Only
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