GABA-immunoreactive neurons in the mushroom bodies of the honeybee: An electron microscopic study

Ganeshina, Olga and Menzel, Randolf (2001) GABA-immunoreactive neurons in the mushroom bodies of the honeybee: An electron microscopic study. The Journal of Comparative Neurology, 437 3: 335-349. doi:10.1002/cne.1287


Author Ganeshina, Olga
Menzel, Randolf
Title GABA-immunoreactive neurons in the mushroom bodies of the honeybee: An electron microscopic study
Journal name The Journal of Comparative Neurology   Check publisher's open access policy
ISSN 0021-9967
Publication date 2001-08-27
Sub-type Article (original research)
DOI 10.1002/cne.1287
Volume 437
Issue 3
Start page 335
End page 349
Total pages 15
Place of publication USA
Publisher John Wiley & Sons
Language eng
Subject 1109 Neurosciences
Abstract Synaptic contacts of γ-aminobutyric acid (GABA) -immunoreactive neurons in honeybee mushroom bodies were studied by using electron microscopic immunocytochemistry. In the lip region of the calyx neuropil, GABA-immunoreactive profiles formed synapses onto both small postsynaptic profiles (76%) and large immunonegative boutons (4%), which were likely to belong to the intrinsic and extrinsic mushroom body neurons, respectively. Three morphologic types of the large immunonegative boutons were distinguished: “light,” “dark,” and “dense core”; all of them received synaptic inputs from the GABA-immunoreactive profiles. A significant proportion of the synapses formed by the GABA-immunoreactive neurons in the lip region (20%) were input synapses from immunonegative neurons. Analysis of thin serial sections showed that the output and input synapses formed microcircuits in which both large immunonegative boutons and small postsynaptic profiles were involved. We interpret these findings to show that negative feedforward and feedback loops exist within the microcircuits of the lip region. J. Comp. Neurol. 437:335–349, 2001. © 2001 Wiley-Liss, Inc.
Keyword GABA
postembedding EM-immunocytochemistry
microcircuits
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Biomedical Sciences Publications
 
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Created: Wed, 12 Apr 2006, 18:38:27 EST