Lipid formulations of Amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system Cryptococcosis

Sun, Hsin-Yun, Alexander, Barbara D., Lortholary, Olivier, Dromer, Francoise, Forrest, Graeme N., Lyon, G. Marshall, Somani, Jyoti, Gupta, Krishan L., del Busto, Ramon, Pruett, Timothy L., Sifri, Costi D., Limaye, Ajit P., John, George T., Klintmalm, Goran B., Pursell, Kenneth, Stosor, Valentina, Morris, Michelle I., Dowdy, Lorraine A., Munoz, Patricia, Kalil, Andre C., Garcia-Diaz, J, Orloff, Susan, House, Andrew A., Houston, Sally, Wray, Dannah, Huprikar, Shirish, Johnson, Leonard B., Humar, Atul, Razonable, Raymund R., Husain, Shahid and Singh, Nina (2009) Lipid formulations of Amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system Cryptococcosis. Clinical Infectious Diseases, 49 11: 1721-1728. doi:10.1086/647948


Author Sun, Hsin-Yun
Alexander, Barbara D.
Lortholary, Olivier
Dromer, Francoise
Forrest, Graeme N.
Lyon, G. Marshall
Somani, Jyoti
Gupta, Krishan L.
del Busto, Ramon
Pruett, Timothy L.
Sifri, Costi D.
Limaye, Ajit P.
John, George T.
Klintmalm, Goran B.
Pursell, Kenneth
Stosor, Valentina
Morris, Michelle I.
Dowdy, Lorraine A.
Munoz, Patricia
Kalil, Andre C.
Garcia-Diaz, J
Orloff, Susan
House, Andrew A.
Houston, Sally
Wray, Dannah
Huprikar, Shirish
Johnson, Leonard B.
Humar, Atul
Razonable, Raymund R.
Husain, Shahid
Singh, Nina
Title Lipid formulations of Amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system Cryptococcosis
Journal name Clinical Infectious Diseases   Check publisher's open access policy
ISSN 1058-4838
Publication date 2009-12
Sub-type Article (original research)
DOI 10.1086/647948
Volume 49
Issue 11
Start page 1721
End page 1728
Total pages 8
Place of publication United States
Publisher Oxford University Press
Language eng
Abstract Synergistic interactions were observed between CIs and antifungal agents against 53 (90%) of 59 Cryptococcus neoformans isolates from solid organ transplant recipients with cryptococcosis and may account for better outcomes in patients with cryptococcosis receiving these immunosuppressive agents.
Keyword Invasive Fungal-Infections
Hematopoietic Stem-Cell
Neoformans Infection
Meningitis
Combination
Aids
Prophylaxis
Management
Toxicity
Ambisome
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: ERA 2012 Admin Only
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